Researchers Learn How a Drug Called Zotatifin Kills Cancer Cells
A cancer drug developed ten years ago at UCSF can also put the brakes on one of prostate cancer's deadliest molecular tricks.

University of California San Francisco
Give to UCSFA cancer drug developed ten years ago at UCSF can also put the brakes on one of prostate cancer's deadliest molecular tricks.
Thousands of people at UCSF work with the purpose of offering hope for the future of every child. Gabby, HT and Brooklyn are among the thousands whose lives have been changed by the research that springs from UCSF’s mission.
Locating seizure onset zones is a critical requirement for epilepsy surgery. This often relies upon intracranial recordings, but finding the exact zone can still present challenges. An experimental study capturing seizures on grid electrode arrays of varying density found that higher density grid arrays produced more specificity in seizure onset areas.
A transformation years in the making has finally arrived at Esprit Park in San Francisco’s Dogpatch neighborhood, driven by a significant investment from UC San Francisco and the dedication of a passionate and growing community.
Orthopedic surgery experts from UCSF Health will present new clinical research findings and cutting-edge surgical techniques at the American Academy of Orthopaedic Surgeons’ (AAOS) annual meeting.
To help patients recover more quickly, hospitals may provide physical and occupational therapy – especially for older adults to help them preserve or regain function. How much therapy is best, though, isn’t clear.
The Bronchiectasis and NTM Association has accepted UC San Francisco (UCSF) into its Bronchiectasis and NTM Care Center Network (CCN), recognizing UCSF’s dedication to providing high-quality medical
Carolyn, a UCSF pathology professor, founded a 100+ member women's physician-scientist group. It fosters collaboration and provides support to empower women across the university.
UCSF received $815 million in awards from the National Institutes of Health (NIH) last year for research that will improve the lives of patients in the U.S. and around the world.
Patients who struggle to take daily HIV pills can benefit from long-acting injectable treatments, a new study by researchers at UC San Francisco has found.
A paralyzed man was able to move a robotic arm and fingers simply by imagining himself doing so, with the help of brain signals decoded through a computer.
Why do women's brains fare better in aging than men's? A study found that the second, 'silent' X chromosome turns on in the brain of old female mice and improves learning and memory – opening new paths to slow the decline in men and women.
Martin Kampmann, PhD, and Anna Victoria Molofsky, MD, PhD, are the 2025 recipients of the Bowes Biomedical Investigator award, which supports scientists who take novel approaches and have the potential to make significant contributions to biomedicine. Recipients receive $1.25 million over five years.
Tuberculosis has stalked humanity for as nearly as long as we've been on earth. In this article, we take a look at how UCSF is leading the fight against the leading infectious disease killer.
Three new construction cranes have arrived at UCSF's Parnassus Heights campus, marking a major milestone in the construction of the new UCSF Health Helen Diller Hospital and UCSF Barbara and Gerson Bakar Research and Academic Building. The cranes will be used to lift materials and equipment for the new buildings, which are scheduled to open in 2028 and 2030, respectively.
A Q&A w/Alison Cohen, PhD, MPH, who is among the estimated 5% of the population with Long COVID. She talks through the implications of Long COVID, and how she applies her scientific and personal experience to research this debilitating condition.
COPA syndrome causes lung hemorrhaging starting in childhood. But one in three people with the disease mutation are spared. UCSF scientists have discovered how a separate gene variant protects those relatives – lighting the way to a possible cure.
A new UCSF study shows that the human lungs have just as many blood-producing stem cells as bone marrow. These stem cells are a precious resource for a variety of therapies for conditions like leukemia or lung diseases.
How did humans evolve brains capable of complex language, civilization, and more? Scientists at UC San Francisco recently found that parts of our chromosomes have evolved at breakneck speeds to give us an edge in brain development compared to apes.
Is artificial turf increasing your risk of injury? UCSF’s chief of the sports medicine and shoulder service Brian Feeley, MD, talks to us about mounting evidence that it does on the heels of his recent study.
Brian T. Feeley, MD, FAOSS, UCSF orthopaedic surgeon and researcher, has been awarded the 2025 Kappa Delta Elizabeth Winston Lanier Award by American Academy of Orthopaedic Surgeons (AAOS). He was
The FDA has approved an adaptive deep brain stimulation (aDBS) treatment for people with with Parkinson’s disease, making this groundbreaking technology available to people nationwide.
UCSF Health intends to continue regular operations, including emergency care, and expects to be able to maintain the majority of scheduled appointments and surgeries during upcoming strike action.
UCSF Health has opened the Peninsula Outpatient Center in downtown Burlingame to bring the health system’s world-class specialty and cancer care close to home with a fifth location on the Peninsula.
UCSF study finds that less than half of homeless individuals regularly use illicit drugs, with methamphetamines being more common than opioids, and many struggle to access treatment.
UCSF scientists have found that some cancers, like brain cancer, make unique, jumbled proteins that make them stand out. These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors.
A study found that B12 requirements may be too low for some people, putting them at risk for cognitive decline.
Saras Ramanathan, MD, has been appointed as editor-in-chief of the Journal of Academic Ophthalmology (JAO). JAO is the official publication of the Association of University Professors of Ophthalmology