Researchers Find a New Way to Visualize Integrins
A collaboration between three labs at UCSF has resulted in an unprecedented look at a member of a vital and ubiquitous class of proteins called integrins.
University of California San Francisco
Give to UCSFA collaboration between three labs at UCSF has resulted in an unprecedented look at a member of a vital and ubiquitous class of proteins called integrins.
A comprehensive genetic analysis of metastatic prostate cancer has, for the first time, revealed a number of major ways in which abnormal alterations of the genome propel this aggressive form of the disease.
Follow-up imaging for women with non-metastatic breast cancer varies widely across the country, according to a new study led by researchers at UCSF.
In an achievement that has significant implications for research, medicine, and industry, UCSF scientists have genetically reprogrammed human immune cells without using viruses to insert DNA
UCSF researchers have identified the sequence of genetic changes that transform benign moles to into malignant skin cancer.
The already famous CRISPR system allows scientists to edit faulty genes by cutting and replacing sections of DNA, but new and improved CRISPR techniques developed at UCSF have expanded CRISPR’s scalpel into a Swiss Army knife.
Scientists have used ultra-high-resolution cryo–electron microscopy to capture the most detailed portrait ever of an opioid drug triggering the biochemical signaling cascade that gives it its power.
Forty percent of deaths attributed to cardiac arrest are not sudden or unexpected, and nearly half of the remainder are not arrhythmic – the only situation in which CPR and defibrillators are effective.
Silicon Valley is helping researchers like Wendell Lim move basic science breakthroughs into translational applications, making treatments available to patients faster than normally possible.
The journey from discovering and developing effective, precise medications to using them correctly and safely in patients is hardly fast and easy. Nor is it a straight shot. Scientists in the UCSF School of Pharmacy are challenging the status quo every step of the way.
Researchers have demonstrated the ability to program groups of individual cells to self-organize into multi-layered structures reminiscent of simple organisms or the first stages of embryonic development.
UCSF researchers have shown that an experimental brain boosting drug, ISRIB, acts like a molecular staple, pinning together parts of a much larger protein involved in cellular stress.
A type of AI known as advanced machine learning can classify essential views from heart ultrasound tests faster, more accurately and with less data than board-certified echocardiographers.
Women bicycle riders are more likely to experience urinary tract infections, genital numbness and saddle sores, but not more likely to have serious sexual and urinary symptoms than non-cyclists.
UCSF received more than $593.9 million in federal funding from the National Institutes of Health in 2017 for research across multiple health-science arenas at the University.
In older men who survived low-risk cancer and have limited life expectancy, frequent PSA screenings may do more harm than good
For the first time, neuroscientists have identified “anxiety” cells deep inside the brain.
A scientifically based approach that includes a tooth-decay risk assessment, aggressive preventive measures and conservative restorations can dramatically reduce decay in community dental practices.
UCSF bioengineers have shown that many of the complex folded shapes that form mammalian body plans and internal tissue structures can be recreated with very simple instructions.
UCSF: The Campaign is taking on the world’s most complex health challenges, powered by an exceptional community of mavericks, innovators, and advocates. Together we will make the Bay Area and our world healthier for all.
Today’s lasers are fine-tuned instruments that can safely and painlessly remove cavities and prevent cavities before they start.
UCSF researchers are leading a resolution revolution by capturing the inner workings of the human body in exquisite images through recent advances in cryo-electron microscopy.
Researchers at UC San Francisco, the University of North Carolina-Chapel Hill, and Stanford University report a major step toward designing more powerful psychiatric drugs with fewer side effects.
UCSF researcher Saul Kato is using a new high-resolution whole-brain imaging technique to see how the entire nervous system of a worm works together to generate behavior.
Newly developed microscopy techniques have allowed UC San Francisco researchers to observe white blood cells in action in unprecedented detail.
Sarah Engelberth won the second annual UCSF Postdoc Slam for her talk about research to generate a material that mimics natural enamel.
Alcohol abuse, dental conditions and depression were among the top causes of avoidable emergency room visits nationally.
UCSF scientists have developed an imaging tool that could soon allow doctors to locate and visualize bacterial infections in the body.
UCSF scientists have mapped in exquisite detail a protein complex called NOMPC, which acts as a mechanoreceptor in animals from fruit flies to fish and frogs.
A new study by UCSF researchers revealed the intriguing possibility that HP1α binds to stretches of DNA and pulls it into droplets that shield the genetic material inside from the molecular machinery of the nucleus that reads and translates the genome.