Myocarditis in Cancer Patients Is Driven by Specific Immune Cells
Researchers have identified specific immune cells that drive deadly heart inflammation in a small fraction of patients treated with powerful cancer immunotherapy drugs.
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Fatty Liver Linked to Survival in E. Coli Infection
Scientists at UCSF have developed a new way of looking at sex-biased diseases that is rooted in evolutionary biology.
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Marijuana, Meth, Cocaine and Opiate Use are Linked to Atrial Fibrillation
A new UCSF study researchers of more than 23 million people concludes that some commonly used and abused drugs pose previously unidentified risks for the development of atrial fibrillation (AF), a potentially deadly heart-rhythm disorder.
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Small-Molecule Drug Reverses Neural Effects of Concussion
A small molecule called ISRIB that was identified at UCSF can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research found.
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Marijuana Use Linked to Atrial Fibrillation in New UCSF Study
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New Industry Documents Highlight Role of Pharmacies in Driving Opioid Epidemic
Johns Hopkins University and UCSF, have added new documents to the Opioid Industry Documents Archive that detail the role of retail pharmacies in the opioid overdose epidemic.
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Single-Celled Organism Uses Internal ‘Computer’ to Walk
The single-celled protozoan Euplotes eurystomus achieves a scurrying walk by coordinate its microscopic uses a simple, mechanical computer instead of a brain like most animals, UCSF researchers found.
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Non-Opioid Compounds Squelch Pain Without Sedation
A newly identified set of molecules alleviated pain in mice while avoiding the sedating affect that limits the use of opiates, according to a new study led by researchers at UC San Francisco.
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UCSF Researchers Discover How Vascular Cells Develop in Prenatal Brain
UCSF has revealed how blood vessel cells develop in the prenatal human brain, paving the way to fully understand the role of these cells in healthy brain development and disease.
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A Drug Based on LSD Appears to Treat Depression in Mice Without the Psychedelic Trip
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LSD-Like Molecules Counter Depression Without the Trip
Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that lasted up to two weeks.
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Drug Turns Cancer Gene Into ‘Eat Me’ Flag for Immune System
A new therapy pulls forward a mutated version of the KRAS protein to help the immune system recognize and destroy cancer cells.
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Pregnant Women Exposed to Cancer-Causing Chemicals in Dishware, Hair Coloring, Plastics, and Pesticides
Pregnant women in the U.S. are being exposed to chemicals like melamine, cyanuric acid, and aromatic amines that can increase the risk of cancer and harm child development, according to a study from researchers at UCSF and Johns Hopkins Bloomberg School of Public Health.
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A.I. Predicts the Shape of Nearly Every Protein Known to Science
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When Are Expired Drugs Truly Expired?
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New Documents Show McKinsey’s Role in Opioid Epidemic
The Opioid Industry Documents Archive (OIDA), a project of UCSF, and Johns Hopkins University, today released more than 114,000 documents related to McKinsey & Company's work as a management consulting firm for the opioid industry.
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The Nobel-Winning Discoveries Illuminating How We Sense the World
How David Julius and Ardem Patapoutian found the molecules in our bodies that sense heat, cold, touch, and pain – and transformed sensory neuroscience.
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UCSF Cancer Specialists to Present Clinical Findings at Major Conference
The latest advances in cancer care and research will be showcased at the annual American Society of Clinical Oncology (ASCO) Annual Meeting, the world’s largest clinical cancer meeting.
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Using Antibiotics To Prevent STIs Found Effective in Early S.F. Study Results
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Doxycycline After Unprotected Sex Significantly Reduced STIs
A significant proportion of bacterial sexually transmitted infections – gonorrhea, chlamydia, or syphilis – were prevented with a dose of doxycycline after unprotected sex, according to preliminary results of a clinical trial.
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UCSF Readying Itself to Tackle Future Pandemics
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Opioid Industry Archive Releases 1.4M Documents from Leading Opioid Maker Implicated in Drug Crisis
UCSF and Johns Hopkins University announced the addition of 1.4 million documents to their Opioid Industry Documents Archive from Mallinckrodt, a leading generic opioid manufacturer now in bankruptcy.
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COVID Drug May Also Ease Symptoms of Long COVID
An antiviral drug approved for high-risk COVID patients may also benefit those with long COVID, according to the findings of a small case series that need to be confirmed with future rigorous studies.
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Evidence Mounts for Need To Study Pfizer’s Paxlovid for Long COVID - Researchers Say
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How the Discovery of an Alzheimer’s Tipping Point Could Improve Drug Trials
In a study, UCSF neurologist William Seeley, MD, and colleagues identified two key moments in the natural history of Alzheimer’s, pointing to a window of opportunity for treatment with amyloid-lowering drugs.
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Seniors with Memory Issues Take Multiple Medications, but Most Are Willing to Cut Down
55% of seniors with dementia take more than six medications even though most have good health. However, a UCSF study showed that 87% are willing to cut down if their doctors agree.
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Treating Tough Tumors by Exploiting Their Iron ‘Addiction’
UCSF researchers successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about one in four cancer deaths.
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Solving the Mystery of a Stubborn – and Common – Cancer Gene
Mark Moasser, MD, has sorted out why HER2, the protein driving 1 in 5 breast cancers, is so hard to drug. He explains how the findings correct a naive way of envisioning how HER2 is shaped and how it works.
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Immune Cells Leave Fingerprints on Tumors Metastasized to the Brain, Offering Clues to Future Therapies
Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types.
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Drug Offers New Hope to Select Patients with ALS, UCSF-CPMC Study Shows
A UCSF-led study found a new drug for ALS that shows to slow or temporarily stall the progression of ALS in a select group of patients, with three times as many patients' disease slowing compared to those who received a placebo.
