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Researchers at UCSF have shown it is possible to make new proteins that move and change shape like those in nature. This ability will help scientists engineer proteins in powerful new ways to treat disease, clean up pollution, and increase crop yields.
Leading cancer researchers from UC San Francisco presented talks about advances in targeted therapies, cancer genomics, using AI to personalize cancer treatment, improving diagnosis of hard-to-treat
Sodium-glucose cotransporter-2 inhibitors (SGLT2i), or gliflozins, are medications used in the treatment of type 2 diabetes mellitus (T2DM). They are designed to lower high blood glucose levels
A team at UCSF and Gladstone Institutes developed new drug candidates that show great promise against the virus that causes COVID-19 and potentially other coronaviruses that could cause future pandemics.
Neuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences.
Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.
A cancer drug developed ten years ago at UCSF can also put the brakes on one of prostate cancer's deadliest molecular tricks.
UCSF received $815 million in awards from the National Institutes of Health (NIH) last year for research that will improve the lives of patients in the U.S. and around the world.
Patients who struggle to take daily HIV pills can benefit from long-acting injectable treatments, a new study by researchers at UC San Francisco has found.
Tuberculosis has stalked humanity for as nearly as long as we've been on earth. In this article, we take a look at how UCSF is leading the fight against the leading infectious disease killer.
UCSF scientists discover how cancer cells hijack the protein factory of the cell to churn out MYC protein, the driver of 70% of all cancers.
During COVID-19, researchers found that low-dose buprenorphine initiation for fentanyl users was largely unsuccessful, with repeated attempts also failing.
An extended course of Paxlovid appears to help some patients with long COVID, according to a study by UCSF researchers that suggests this treatment option holds promise for some of those struggling with lasting symptoms.
Nearly 50 UCSF researchers have been named to Clarivate’s list of most influential scientists for 2024.
UCSF researchers develop customizable SNIPR sensors that activate engineered cells only near tumors, promising precise cancer therapies with minimal side effects.
New drugs and therapies have become indispensable for treating an array of cancers. Unfortunately, they can also cause damage to the heart, a side effect that has led to the development of a new
With the help of up to $30M in funding, researchers led by UCSF’s James Fraser, PhD, will use AI to map drug “anti-targets,” aiming to speed up drug development and reduce costs.
A new study on doxy-PEP sheds light on whether people who are regular users become resistance to this treatment, which often serves as a “morning after” pill to prevent sexually transmitted diseases.
Breast cancer is the second leading cause of cancer deaths in the U.S. and worldwide, pointing to the continuing need to improve treatment strategies and therapies that better patient survival and
A talk on how breathing affects our mood took first place at this year's Postdoc Slam event, which is held in celebration of National Postdoc Appreciation Week.
Powerful electron microscopy and 3D imaging leads scientists to a new discovery showing how the TGF-Beta signaling protein is able to move much more freely than previously thought.
A clinical trial that will test three drugs concurrently, and could include more, represents new hope for patients with progressive supranuclear palsy (PSP), an incurable neurodegenerative disorder that usually kills within seven years after symptoms start.
Aashish Manglik delivered the 29th annual Byers Award Lecture titled “Signal Reception: Cracking Codes in Cellular Communication.”
Scientists at UCSF and Contineum Therapeutics have developed a drug that spurs the body to replace the protective insulation around nerve cells, myelin, that is lost in multiple sclerosis. If it works in people, it could be a way to reverse the damage caused by the disease.
Added sugar in diet can speed up epigenetic aging, while a sustained, healthy diet with can slow it down and possibly reverse biological aging.
A newly discovered hormone explains why females can maintain bone density during lactation, when calcium is stripped away to make milk. This discovery could one day have applications to treating fractures, osteoporosis, and other bone diseases.
Ultrasound is not necessary for medication abortion, and patients do equally well whether they are seen in person or via telehealth, and whether they receive their medication in person or through a mail order pharmacy.
