University of California San Francisco
Give to UCSFAs people around the world try to envision recovery from the COVID-19 pandemic, much attention has been paid to antibody testing as a way to identify people who have developed immunity to the virus. UCSF experts explain how antibody testing works, who it can be most useful for and why we should be cautious.
While the widely used coronavirus PCR tests take about four hours to produce a result from a respiratory sample, the new DETECTR test developed by UCSF scientists takes only 45 minutes, rapidly accelerating the pace of diagnosis.
Though many hopes are hanging on the development of a vaccine or drug that targets the novel coronavirus directly, a UCSF-led team is taking an unconventional approach: target the host – in other words, you.
A simple urine test can diagnose and predict acute rejection in kidney transplants, leading to an opportunity for earlier detection and treatment, according to a new study by researchers at UCSF.
UC San Francisco researchers have finally identified the cellular circuit responsible for conveying stress signals from inside mitochondria to the integrated stress response, a discovery that may have important implications for treating the many debilitating diseases associated with mitochondrial stress.
A new UCSF study of patients with Parkinson’s disease has revealed a pathway that transmits signals very rapidly between two parts of the human brain to govern the complex act of halting a motion once it’s been initiated.
UCSF scientists have made a significant advance toward understanding a rare genetic condition, almost exclusively affecting females, that results in a broad spectrum of neurodevelopmental deficits.
A simple blood test may soon be able to diagnose patients with two common forms of dementia – Alzheimer’s disease and frontotemporal dementia – and tell the two apart.
A blood test that may eventually be done in a doctor’s office can swiftly reveal if a patient with memory issues has Alzheimer’s disease or mild cognitive impairment and can also distinguish both conditions from frontotemporal dementia.
Administering stem cell or enzyme therapy in utero may be a path to alleviating some congenital diseases that often result in losing a pregnancy, according to a new study in mice by UCSF researchers. They showed that stem cells can enter the fetal brain during prenatal development and make up for cells that fail to make an essential protein.
Researchers screened a massive library of over 150 million virtual molecules and discovered the first drugs that selectively target one of two mammalian melatonin receptors that modulate sleep-wake cycles.
For a conditioned response to become long-lasting requires brain cells to increase amounts of an insulating material called myelin, which may serve to reinforce and stabilize newly formed neural connections.
Survival may more than double for adults with glioblastoma, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor.
Understanding the biological differences that drive distinct symptoms of Alzheimer’s disease could lead to more personalized patient care and potentially therapies targeted to patients’ individual needs.
In a study of rats navigating a simple maze, neuroscientists at UCSF have discovered how the brain may generate such imagined future scenarios. The work provides a new grounding for understanding not only how the brain makes decisions but also how imagination works more broadly, the researchers say.
Widely used organoid models fail to replicate even basic features of brain development and organization, much less the complex circuitry needed to model complex brain diseases or normal cognition.
UCSF–led research team has discovered the first conclusive evidence that natural selection may also occur at the level of the epigenome and has done so for tens of millions of years.
Scientists at UCSF are exploring how we can improve our bodies – now and in the future – with science that sounds like sci-fi.
English and Italian speakers with dementia-related language impairment experience distinct kinds of speech and reading difficulties based on features of their native languages.
A physically and mentally active lifestyle confers resilience to frontotemporal dementia, even in people whose genetic profile makes the eventual development of the disease virtually inevitable.
The breakthroughs came as Jack Levin was trying to find out if the cells normally circulating in the horseshoe crab’s blood, called amebocytes, triggered clotting, as platelets do in human blood.
UCSF postdoctoral researcher for the first time succeeded in keeping a diverse array of glioblastomas alive in the lab using brain organoids