University of California San Francisco
Give to UCSFA new method of comparing massive numbers of CAR-T cells can determine which is most effective and long-lasting against cancer.
Immune checkpoint inhibitors (ICIs) used in cancer care can cause myocarditis, a potentially fatal side effect, and it appears that the adverse cardiac effects may disproportionally impact female patients.
A new diagnostic method that applies machine learning to advanced genomics data from both microbe and host to identify and predict sepsis cases was developed by researchers at UCSF, the Chan Zuckerberg Initiative, and CZ Biohub.
Last month new “bivalent” booster vaccines made by Moderna and Pfizer became available that protect against currently circulating Omicron variants as well as earlier strains of the SARS-CoV-2 virus that causes COVID-19. This Q&A features Joel Ernst, MD, a UCSF professor of medicine whose research aims to understand how pathogens evade the immune system.
UCSF has revealed how blood vessel cells develop in the prenatal human brain, paving the way to fully understand the role of these cells in healthy brain development and disease.
A new therapy pulls forward a mutated version of the KRAS protein to help the immune system recognize and destroy cancer cells.
UCSF-led research outlines the comprehensive immune landscape and microbiome of pancreatic cysts as they progress from benign cysts to pancreatic cancer. Their findings could reveal the mechanism of neoplastic progression and provide targets for immunotherapy to inhibit progression or treat invasive disease.
A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications. The approach, developed at Gladstone Institutes and UC San Francisco (UCSF), lets scientists introduce especially long DNA sequences to precise locations in the genomes of cells at remarkably high efficiencies without the viral delivery systems that have traditionally been used to carry DNA into cells.
T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.
A new national study led by UCSF found that more sophisticated devices that pair with smartphones don’t lead to better blood pressure control than home-use blood pressure cuffs.
The repercussions of overturning Roe v. Wade – and the failure of the Supreme Court to provide any guidance on exceptions related to the life and health of the mother – are potentially catastrophic for women who face a life-threating diagnosis of pregnancy associated cancers (PAC).
Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UCSF, the University of Pennsylvania and the University of Michigan.
A new "subway map" of immune networks connects gene variation to risk for autoimmune disease.