Next-Gen Precision Diagnostics Now Available at UCSF
A genome sequencing test developed at UCSF that can rapidly pinpoint the cause of a bacterial, viral, fungal or parasitic infection is now available to help physicians nationwide diagnose cases.
University of California San Francisco
Give to UCSFA genome sequencing test developed at UCSF that can rapidly pinpoint the cause of a bacterial, viral, fungal or parasitic infection is now available to help physicians nationwide diagnose cases.
A research team led by scientists at UCSF has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs.
Twenty-six UCSF investigators received funding from the 2017 cycle of the Marcus Program in Precision Medicine Innovation to help generate understanding of human disease.
A molecular test can pinpoint which patients will have a very low risk of death from breast cancer even 20 years after diagnosis and tumor removal, according to a new clinical study led by UCSF in collaboration with colleagues in Sweden.
A new study by UCSF researchers revealed the intriguing possibility that HP1α binds to stretches of DNA and pulls it into droplets that shield the genetic material inside from the molecular machinery of the nucleus that reads and translates the genome.
UCSF researchers have drawn a link between genetic abnormalities in neurodegenerative diseases and the formation of RNA foci, work the scientists said may open avenues to the development of new drug treatments.
A test commonly used in breast cancer has been found to also identify which patients with aggressive prostate cancer will benefit from hormonal therapy.
Researchers made a significant advance, identifying the first “high-confidence” risk gene for Tourette disorder as well as three other probable risk genes.
UCSF researchers have used data-mining computational tools to identify a treatment for hepatocellular carcinoma, a cancer associated with underlying liver disease and cirrhosis that often only becomes symptomatic when it is very advanced.
Christina Hueschen took home the top prize at this year’s UCSF Grad Slam competition for her talk titled “How to Build an Elephant.”
Location-tracking apps on smartphones could be used to help track and manage care for thousands of patients who suffer from chronic diseases, and possibly provide feedback to them on lifestyle changes.
Researcher Annesa Flentje is looking at ways stress among sexual minorities – those whose sexual orientation, identity or practices differ from the majority – can affect physical and mental health, starting at the genetic level, with a particular focus of late on the effect of stress on HIV-positive men.
In an unprecedented leap from lab to patients, a potential treatment for childhood epilepsy identified in experiments with zebrafish.
New research is paving the way to a precision medicine approach to the diagnosis and treatment of patients with traumatic brain injury.
The chromosomal “balance” of normal and abnormal versions of the cancer-driving gene KRAS affects the response to targeted treatments.
A novel gene therapy treatment may save infants from SCID, a devastating immune disorder commonly known as "bubble boy disease".
The genome of the single-celled organism Stentor, recently sequenced by researchers, may help lead to new insights about how to help our own cells and tissues recover from injury.
A nationwide project that includes two UCSF researchers will use the latest technology, including gene editing, to gain insights into human biology that could one day lead to treatments for complex genetic diseases.
A new study identified genetic predictors of normal prostate-specific antigen (PSA) levels in healthy men, which could be used to improve the accuracy of PSA-based prostate cancer screening tests.
Distinct sets of genetic defects in a single neuronal protein can lead either to infantile epilepsy or to autism spectrum disorders.
Study suggests, genetic variants that have distinct effects on physical traits in men versus women are also linked to men’s and women’s risk for a range of diseases – autism, multiple sclerosis, type 1 diabetes.
UCSF study demonstrates that nucleosomes actively change their shape as part of the larger process of epigenetic regulation of gene expression.
UC San Francisco scientists have formed an innovative research alliance with three global pharmaceutical companies.
UC San Francisco’s Center for Digital Health Innovation announced a collaboration with Intel Corporation to deploy and validate a deep learning analytics platform designed to improve care.
Mitochondrial replacement therapy now has been used in humans to conceive a “three-parent baby” to prevent inherited mitochondrial disorders, but there remain questions about the effectiveness of the process.
School of Dentistry Dean John Featherstone, PhD, explains his new philosophy of preventive dentistry.
Children with severe cases of epilepsy such as Dravet syndrome are finding new and unexpected cures thanks to determined pediatricians and translational research at UCSF.
A UC San Francisco-led study has identified signatures of ethnicity in the genome that appear to reflect an ethnic group’s shared culture and environment, rather than its common genetic ancestry.
Steven Altschuler and Lani Wu are using artificial intelligence to spot and label potential medical uses for biological compounds.
UCSF researchers have discovered a way to switch off the widely used CRISPR-Cas9 gene-editing system using newly identified anti-CRISPR proteins that are produced by bacterial viruses.