Shared Mechanisms Allow SARS-CoV-2 Variants to Thrive Post-Vaccination
Convergent evolutionary mechanisms shared by COVID-19 variants allow them to overcome both adaptive and innate immune system barriers.

University of California San Francisco
Give to UCSFConvergent evolutionary mechanisms shared by COVID-19 variants allow them to overcome both adaptive and innate immune system barriers.
Recommendations are in place for the updated COVID-19 vaccine from Pfizer-BioNTech and Moderna.
The FDA recently approved the world’s first vaccines to prevent RSV for infants and elderly adults.
A new report from the Lancet Commission on tuberculosis releases recommendations, providing a path forward to turn the tide on this preventable, treatable and curable disease.
Long COVID symptoms can persist for a year after initial infection, or re-emerge months later after disappearing.
A common mutation can help people infected with the COVID-19 virus avoid developing any symptoms.
Deaths among older adults with dementia fell starkly in nursing homes and long-term care centers after COVID-19 vaccinations became available, but remained high for those living at home.
A short course of antibiotics, Doxy-PEP, can prevent some STIs after condomless sex.
After diagnosing a middle-aged man with an incredibly rare and almost always fatal infection, a medical team led by UCSF fellow Natasha Spottiswoode raced to find a treatment that could save his life.
UCSF infectious disease specialist Michael Peluso, MD, who co-leads one of the world’s oldest studies of long COVID, discusses the condition’s mysteries.
UCSF’s Nevan Krogan, PhD, is taking aim at the world’s deadliest diseases by uniting scientists and the biomedical industry to speed treatments.
Quantitative Biosciences Institute’s Nevan Krogan reflects back on the COVID-19 pandemic and how internal and external communications, funding and international partnerships all contributed to a speedy COVID-19 response.
Two new oral polio vaccines will help limit the amount of new polio strains and outbreaks by genetically engineering weakened polio virus in the oral vaccine to reduce reversion to dangerous forms.
Face masks remain crucial in preventing the spread of COVID-19, even with vaccine availability. The decision to wear masks depends on vaccination status, risk factors, and local hospitalizations. Medical N95, KN95, or KF94 masks offer the best protection.
While some patients recover from the effects of COVID-19, others experience the aftereffects long after the initial infection. UC San Francisco researchers are studying why some COVID-19 patients
COVID vaccine efficacy varied by age, BMI, sex, and smoking status, with levels changing over six months in a UCSF-led study. Pfizer and Moderna had higher antibody responses than Johnson & Johnson at one month, but Johnson & Johnson overtook them at six months.
Avian flu cases are spiking. Will it spill over into humans?
A hepatitis outbreak in children occurred after COVID-19 lockdowns eased in 2022. Sudden exposure to a multitude of viruses upon reopening may have triggered this response in a small group of children.