Risk of Deadly Skin Cancer May Be Gauged by Accumulated DNA Damage
Risk for melanoma, the most deadly skin cancer, can be estimated long before detection of any suspicious moles, according to a UCSF scientist.
University of California San Francisco
Give to UCSFRisk for melanoma, the most deadly skin cancer, can be estimated long before detection of any suspicious moles, according to a UCSF scientist.
Most parents know or suspect when their child smokes, but they are much more likely to be in the dark if the child vapes or uses other tobacco products, according to a large national study by researchers at UCSF.
Though cancer immunotherapy has become a promising standard-of-care treatment – and in some cases, perhaps a cure – for a wide variety of different cancers, it doesn’t work for everyone, and researchers have increasingly turned their attention to understanding why.
Researchers at UCSF are tackling antibiotic resistance using a different approach: redesigning existing antibiotic molecules to evade a bacterium’s resistance mechanisms
Greater maternal stress during pregnancy is linked with significant increases in the number and variety of infant illness during the first year of life, independent of the level of stress after birth.
Researchers have figured out how to assemble genetic profiles of individual lung cancer cells obtained from patients at different times during the course of their treatment.
UCSF scientists now have evidence from research that women with Alzheimer’s live longer than men with the disease because they have genetic protection from the ravages of the disease.
Researchers at UCSF have developed a “digital biomarker” that would use a smartphone’s built-in camera to detect diabetes.
UCSF scientists have devised a novel approach to halting the spread of SARS-CoV-2, the virus that causes the disease.
UCSF researchers have now determined how the TRPA1 molecule manages to sense such a diverse variety of dangerous chemicals – and do so with enough sensitivity to let you flee before suffering too much tissue damage.
Why are more men than women dying of COVID-19? Scientist Faranak Fattahi, PhD, has found a clue.
Two innovative UCSF projects in hydrogel therapies to develop new salivary glands and restore muscle loss after facial injuries have received critical funding to move closer to clinical trials.
The researchers determined "medical vulnerability" by referencing indicators identified by the CDC, including heart conditions, diabetes, current asthma, immune conditions (such as lupus, gout, rheumatoid arthritis), liver conditions, obesity and smoking within the previous 30 days. Additionally, the researchers added e-cigarettes to tobacco and cigar use.
None of the individual tumor genetic differences that were identified are likely to explain significant differences in health outcomes or to prevent Black Americans from benefiting from a new generation of precision prostate cancer therapies, researchers say, as long as the therapies are applied equitably.
A new model of the causes of breast cancer, created by a team led by researchers at UCSF, Genentech and Stanford University, is designed to capture the complex interrelationships between dozens of primary and secondary breast cancer causes and stimulate further research.
Under a new agreement, Celgene will further invest in the RAN’s state-of-the-art antibody engineering program to expand target discovery from oncology and immunology to include neurology.
The finding could offer additional insights into other immune conditions, including a type of childhood leukemia and the severe inflammation response in some children with COVID-19.
Pregnant women with the metabolic condition known as non-alcoholic fatty liver disease have more than four times the risk of serious adverse maternal-fetal outcomes.
Depending on a cancer’s tissue of origin, tumors cause widespread and variable disruption of the immune system throughout the body, not just at the primary tumor site.
Cancer specialists from UCSF will present new research findings at the annual scientific program of the American Society of Clinical Oncology, the world’s largest clinical cancer research meeting.
UCSF researchers have become to the first to solve the structure of a hard-working protein that helps reload neurons for repeated firing.
Smoking significantly worsens COVID-19, according to a new analysis by UCSF of the association between smoking and progression of the infectious disease.
Cancer and autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, might not seem to have much in common, but some researchers now are pinning hopes on the same immune system cell –
As people around the world try to envision recovery from the COVID-19 pandemic, much attention has been paid to antibody testing as a way to identify people who have developed immunity to the virus. UCSF experts explain how antibody testing works, who it can be most useful for and why we should be cautious.
UCSF researchers now have reported a new method to design and test cell therapies, one they expect will speed the development of new life-saving treatments not only for cancer, but for other diseases, too.
Lung damage is the cause of most COVID-19 deaths, and lung damage also is a public health concern for smokers and anybody living under polluted skies.