CRISPR Gene Editing Makes Stem Cells ‘Invisible’ to Immune System
UCSF scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally “invisible” to the immune system.
University of California San Francisco
Give to UCSFUCSF scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally “invisible” to the immune system.
UCSF researchers created a chimpanzee brain “organoids” that mimic the development and organization of full-size brains.
UCSF researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes.
A growing number of researchers at UCSF and elsewhere have turned their attention to questions around why and how some people who age thrive and are more resilient than others.
From sensory processing disorder to how CRISPR is being explored to bring new treatments to patients, these are the stories that most engaged our readers in 2018.
Scientists at UCSF and Boston Children’s Hospital have developed a new technique for making mice with brains that combine the genetics of two different mouse strains.
Experiments using parasitic worms in the mouse gut have revealed a surprising new form of wound repair, a finding that could help scientists develop ways to enhance the body’s natural healing abilities.
A so-called “jumping gene” that researchers long considered either genetic junk or a pernicious parasite is actually a critical regulator of the first stages of embryonic development.
UCSF scientists have shown that in the human hippocampus neurogenesis declines throughout childhood and is undetectable in adults.
UCSF received more than $593.9 million in federal funding from the National Institutes of Health in 2017 for research across multiple health-science arenas at the University.
Loss of an enzyme that modifies gene activity to promote brain regeneration may be partly responsible for age-related cognitive decline, according to new research in laboratory mice by UCSF.
Many researchers have long assumed that most stem cells in the body can produce new cells indefinitely, but new research at UCSF shows that this is not the case in the brain.
UCSF bioengineers have shown that many of the complex folded shapes that form mammalian body plans and internal tissue structures can be recreated with very simple instructions.
Whether you are seeing them for the first time or coming back for another look, check out the most popular scientific stories from UC San Francisco from the past year.
UCSF have taken the first step toward a comprehensive atlas of gene expression in cells across the developing human brain.