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Science in Focus: Using Light to Make Single Cells Self-Destruct

Researchers at UCSF have developed a new optogenetic tool that can be used to completely eliminate single cells from brain networks in animals. The researchers believe the new tool will enable exquisitely precise experiments to help researchers understand how each cell contributes to the whole.

Positive Multiple Sclerosis Clinical Trial Results Support New Treatment Approach

In findings that show the effectiveness of a new strategy for treating multiple sclerosis, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab in both relapsing multiple sclerosis and primary progressive multiple sclerosis.

Science in Focus: How Do White Blood Cells Move So Fast?

White blood cells called neutrophils race after bacteria at speeds up to a thousand times that of most human cells by moving in a special way. Lillian Fritz-Laylin and Megan Riel-Mehan want to know how that works.

FDA Funds UCSF-Stanford Center on Regulatory Science

The U.S. Food and Drug Administration has awarded the UCSF-Stanford Center of Excellence in Regulatory Science and Innovation (UCSF-Stanford CERSI) a five-year grant with up to $25 million in funding.

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Science in Focus: Evolving Immune Fighters in the Gut

Graduate student Lauren Rodda captured a microscopic mage of a mouse gut, which highlights her work to understand the germinal center, where immune cells compete to be the best at recognizing an invading pathogen.

Gene Variant Explains Differences in Diabetes Drug Response

The first results from a large international study of patients taking metformin, the world’s most commonly used type 2 diabetes drug, reveal genetic differences among patients that may explain why some respond much better to the drug than others.