How a Key Protein Juggles Multiple Demands to Keep Neurons Firing
UCSF researchers have become to the first to solve the structure of a hard-working protein that helps reload neurons for repeated firing.
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Resilience to ALS Due to Synaptic Safety Mechanism
UCSF researchers have identified a powerful self-corrective mechanism within synapses that is activated by neurodegeneration and acts to slow down disease progression in animal models of ALS.
More Steps Needed to Manage Current Care of Older Adults
The COVID-19 pandemic is a critical time to think about how best to manage the care of older adults, both for their sake and for the near- and longer-term costs and stresses to the health care system, according to a new commentary by a UCSF clinician.
Cognitive, Functional and Psychological Condition Affect Surgery Risk in Older Patients
Based on findings from a new study, future research should examine how to incorporate functional, cognitive and psychological factors in the pre-surgery assessment of older adults.
Cellular SOS: CRISPR Technique Reveals How Cell’s ‘Power Plants’ Activate Emergency Response
UC San Francisco researchers have finally identified the cellular circuit responsible for conveying stress signals from inside mitochondria to the integrated stress response, a discovery that may have important implications for treating the many debilitating diseases associated with mitochondrial stress.
Superfast Brain Circuit Slams the Brakes on Movement
A new UCSF study of patients with Parkinson’s disease has revealed a pathway that transmits signals very rapidly between two parts of the human brain to govern the complex act of halting a motion once it’s been initiated.
Scientists Unravel Mystery of Rare Genetic Disorder that Causes Intellectual Disability in Females
UCSF scientists have made a significant advance toward understanding a rare genetic condition, almost exclusively affecting females, that results in a broad spectrum of neurodevelopmental deficits.
Simple Blood Test May be Able to Diagnose Alzheimer’s Disease
A simple blood test may soon be able to diagnose patients with two common forms of dementia – Alzheimer’s disease and frontotemporal dementia – and tell the two apart.
Memory Concerns? Blood Test May Put Mind at Ease or Pave Way to Promising Treatments
A blood test that may eventually be done in a doctor’s office can swiftly reveal if a patient with memory issues has Alzheimer’s disease or mild cognitive impairment and can also distinguish both conditions from frontotemporal dementia.
