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Smarter Drug Delivery with Tejal Desai, PhD

<p>Swallowing pills means medication must face the challenge of surviving the harsh environment of the digestive tract. As a result, people must take larger doses than they need. Using micro and nano-fabrication techniques developed by the computer chip industry, Desai’s lab is creating tiny devices that take multiple drugs directly to where they are needed, using less medication, minimizing side effects and making the process safer for the patient.&nbsp;</p>

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Mining the Human Body with Michael Fischbach, PhD

<p>Having developed an algorithm that discovered a large quantity of drug-producing bacteria in and on humans, Fischbach has turned his lab’s attention to studying their populations and interactions with each other. This, he posits, can greatly influence a person’s overall health and disease.</p>

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Window into the Brain with Adam Boxer, MD, PhD

<p>Many researchers are finding that by the time a patient seeks treatment for symptoms of Alzheimer’s disease, it’s often too late for the available drugs to have an effect. Boxer’s lab is studying very precise eye tracking methods to gauge mental fitness and identify cognitive decline decades before the first symptoms appear.</p>

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UCSF Joins Caltech in Creative Problem Solving to Advance Health Care

<p>Experts at UCSF and Caltech are pushing the boundaries of creative problem solving to address important clinical problems with the hope that the talent pool at both institutions, combined with an entrepreneurial spirit, will advance health care innovation.</p>

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Men's and Women's Immune Systems Respond Differently to PTSD

Men and women had starkly different immune system responses to chronic post-traumatic stress disorder, with men showing no response and women showing a strong response, in two studies by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

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UCSF Team Shows How to Make Skinny Worms Fat and Fat Worms Skinny

Researchers exploring human metabolism at UCSF have uncovered a handful of chemical compounds that regulate fat storage in worms, offering a new tool for understanding obesity and finding future treatments for diseases associated with obesity.

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Asthma Tied to Bacterial Communities in the Airway

Asthma may have a surprising relationship with the composition of the species of bacteria that inhabit bronchial airways, a finding that could suggest new treatment or even potential cures for the common inflammatory disease, according to a new UCSF-led study.

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UCSF Team Views Genome As It Turns On and Off Inside Cells

UCSF researchers have developed a new approach to decoding the vast information embedded in an organism’s genome, while shedding light on exactly how cells interpret their genetic material to create RNA messages and launch new processes in the cell.

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New Imaging Advance Illuminates Immune Response in Breathing Lung

In a recent UCSF-led study in mice, researchers developed a method to stabilize living lung tissue for imaging without disrupting the normal function of the organ. The method allowed the team to observe, for the first time, both the live interaction of living cells in the context of their environment and the unfolding of events in the immune response to lung injury.

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