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Vitamin C Helps Control Gene Activity in Stem Cells

A UCSF-led team has discovered that vitamin C affects whether genes are switched on or off inside mouse stem cells, suggesting that it may play fundamental role in helping to guide normal development.

Nobel Prize Rockets Stem Cell Program to New Heights

Shinya Yamanaka's Nobel Prize for stem cell research brought fresh attention to something UCSF long ago sensed and seized: the promise of regeneration medicine for repairing or replacing damaged cells, tissues, and even whole organs.

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Transplanted Neural Stem Cells Produced Myelin, UCSF Study Shows

For the first time, a clinical trial led by UCSF investigators and sponsored by Stem Cells Inc., has shown that transplanted neural stem cells appear to produce myelin in the brains of four young children with an early-onset, fatal disease.

Neural Stem Cell Study Arose from Culture of Collaboration That Drives Clinical Innovation

<p>A new study that represents a significant first step in exploring the potential of stem cells to treat neurological disease is a “natural outgrowth” of a longstanding culture of interdisciplinary collaboration in UCSF neonatology — a culture that UCSF Benioff Children's Hospital physicians David Rowitch and Donna Ferriero&nbsp;work hard to sustain.</p>

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Frequently Asked Questions About Stem Cell Science

<p>Here are answers to frequently asked questions about induced pluripotent stem cells, or iPS cells, the type of cell that has been reprogrammed from an adult cell, such as a skin or blood cell.</p>

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Shinya Yamanaka Wins 2012 Nobel Prize in Medicine

<p>Shinya Yamanaka, MD, PhD, a senior investigator at the Gladstone Institutes and a professor of anatomy at UCSF, has won the 2012 Nobel Prize in Physiology or Medicine for his discovery of how to transform ordinary adult skin cells into cells that are capable of developing into any cell in the human body.</p>

Gladstone Scientists Reprogram Skin Cells into Brain Cells

Scientists at the Gladstone Institutes have for the first time transformed skin cells — with a single genetic factor — into cells that develop on their own into an interconnected, functional network of brain cells.

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Stem Cell Odyssey Leads from Tusks and Teeth to Gut

<p>Medical geneticist Ophir Klein's studies of stem cells in tooth development and of stem cell changes in the gut may lead to new strategies for regenerating teeth and for treating craniofacial abnormalities.</p>

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