Researchers Develop Stem Cell Therapies for Acute Lung Injury
A team of UCSF researchers developing cell-based therapies for acute respiratory distress syndrome benefited from advisors who helped identify gaps in their development plan.
University of California San Francisco
Give to UCSFA team of UCSF researchers developing cell-based therapies for acute respiratory distress syndrome benefited from advisors who helped identify gaps in their development plan.
Stem-cell researchers at UCSF have found a key role for a protein called BMI1 that may help scientists direct the development of tissues to replace damaged organs in the human body.
A UCSF-led team has discovered that vitamin C affects whether genes are switched on or off inside mouse stem cells, suggesting that it may play fundamental role in helping to guide normal development.
Raising hopes for cell-based therapies, UCSF researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory.
Shinya Yamanaka's Nobel Prize for stem cell research brought fresh attention to something UCSF long ago sensed and seized: the promise of regeneration medicine for repairing or replacing damaged cells, tissues, and even whole organs.
Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UCSF scientists have found.
Stem cells of the aging bone marrow recycle their own molecules to survive and keep replenishing the blood and immune systems as the body ages, UCSF researchers have discovered.
For the first time, a clinical trial led by UCSF investigators and sponsored by Stem Cells Inc., has shown that transplanted neural stem cells appear to produce myelin in the brains of four young children with an early-onset, fatal disease.
<p>A new study that represents a significant first step in exploring the potential of stem cells to treat neurological disease is a “natural outgrowth” of a longstanding culture of interdisciplinary collaboration in UCSF neonatology — a culture that UCSF Benioff Children's Hospital physicians David Rowitch and Donna Ferriero work hard to sustain.</p>
<p>Here are answers to frequently asked questions about induced pluripotent stem cells, or iPS cells, the type of cell that has been reprogrammed from an adult cell, such as a skin or blood cell.</p>
<p>Shinya Yamanaka, MD, PhD, a senior investigator at the Gladstone Institutes and a professor of anatomy at UCSF, has won the 2012 Nobel Prize in Physiology or Medicine for his discovery of how to transform ordinary adult skin cells into cells that are capable of developing into any cell in the human body.</p>
Gladstone Institutes Senior Investigator Shinya Yamanaka, MD, PhD, a professor of anatomy at UCSF, has won the Millennium Technology Award Grand Prize, the world’s largest and most prominent technology award.
Scientists at the Gladstone Institutes have for the first time transformed skin cells — with a single genetic factor — into cells that develop on their own into an interconnected, functional network of brain cells.
<p>Medical geneticist Ophir Klein's studies of stem cells in tooth development and of stem cell changes in the gut may lead to new strategies for regenerating teeth and for treating craniofacial abnormalities.</p>