University of California San Francisco
Give to UCSFSynuclein is a protein that can cause Parkinson’s disease, although it is not clear how. UCSF researcher Robert Edwards, MD, now has discovered that synuclein can affect signal transmission between nerve cells long before disease symptoms arise.
In neurodegenerative diseases, clumps of insoluble proteins appear in patients’ brains. These aggregates contain proteins that are unique to each disease, such as amyloid beta in Alzheimer’s disease, but they are intertwined with small amounts of many other insoluble proteins that are normally present in a soluble form in healthy young individuals.
A commercial brain fitness program has been shown to improve memory in older adults, at least in the period soon after training. The findings are the first to show that practicing simple visual tasks can improve the accuracy of short-term, or “working” visual memory.
The Veterans Health Research Institute or NCIRE will present “The Brain at War: Neurocognitive Consequences of Combat” today (June 17).
James McKerrow, leader of the Sandler Center for Drug Discovery at UCSF, was honored with the 2009 Mendel Medal for his work identifying the vulnerabilities of disease-causing parasites and for devising new strategies to fight them.
Undergraduate students from as far away as Fresno came to UCSF recently for an inside look at one of the nation’s best graduate schools.
UCSF researchers have created the first transgenic mouse to display the earliest signs of Parkinson’s disease using the genetic mutation that is known to accompany human forms of the disease.
A UCSF-led study examining the impact of statins on the progression of multiple sclerosis found a lower incidence of new brain lesions in patients taking the cholesterol-lowering drug in the early stages of the disease as compared to a placebo.
A new report by the Institute of Medicine has found that military service in the Persian Gulf War is a cause of post-traumatic stress disorder in some veterans.
UCSF scientists have used a novel cell-based strategy to treat motor symptoms in rats with a disease designed to mimic Parkinson’s disease. The strategy suggests a promising approach, the scientists say, for treating symptoms of Parkinson’s disease and other neurodegenerative diseases and disorders, including epilepsy.
People are paying close attention to pediatric endocrinologist Robert Lustig’s message that the obesity epidemic can be blamed on a marked increase in the consumption of a type of sugar called fructose.
A new study co-authored by a UCSF resident physician and published this week examines why low-income countries are making poor progress in meeting international health goals. Study researcher Sanjay Basu, MD, PhD, of the Department of Medicine at UCSF and Division of General Internal Medicine at San Francisco General Hospital, said findings highlight the importance of looking at the entire health experience of a family, rather than just one or a few diseases.
A panel of experts appointed by Mayor Gavin Newsom recently presented an action plan as the approaching “age wave may bring a potential crisis in Alzheimer’s and dementia care” to San Francisco.
A specific region of the hippocampus, a brain structure that is essential to memory, is significantly smaller in veterans with post-traumatic stress disorder than in those without the condition, according to a study by researchers at the San Francisco VA Medical Center and UCSF.