University of California San Francisco
Give to UCSFCells from individuals with Major Depressive Disorder (MDD) were found to have higher than expected rates of methylation at specific sites on their DNA, when compared to cells from healthy individuals without MDD, according to a study by a multidisciplinary team of UCSF, in collaboration with others.
Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient’s own blood-forming stem cells.
A large study of brain MRI scans from 11,679 children between the ages of 9 and 10 reviewed by UC San Francisco neuroradiologists identified potentially life-threatening conditions in 1 in 500
Scientists at UCSF’s Neuroscape brain research center have developed a first-of-its-kind virtual reality video game that can improve memory in healthy, older adults.
We asked UCSF infectious disease expert Monica Gandhi, MD, MPH, to unpack some of the big questions around vaccine science, such as how the Johnson & Johnson vaccine differs, how well it works against the new variants, and whether you should be worried about transmitting the virus after vaccination.
This will be one of the first and largest studies to examine the impact of factors like age and stress on vaccination effectiveness.
In a new study, UCSF and Stanford researchers have identified a central switch that appears to control when neural progenitor cells stop multiplying and start differentiating into mature neurons.
UCSF researchers found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, gain only half the weight of other mice, even if all the mice eat a high-fat diet.
UCSF scientists have formed a research alliance with pharmaceutical firm Eli Lilly and Company aimed at better understanding autoimmune diseases and fostering the development of new therapies
Many cancer patients might respond better to treatments with the help of a new prognostic indicator based on a distinctive pattern of gene activity within tumor cells.
Millie Hughes-Fulford, a UCSF scientist who flew in June 1991 aboard the first space shuttle mission dedicated to biomedical studies, died on Feb. 2 at the age of 75. S
A new study finds that inherited genetic variation plays a role in who is likely to benefit from checkpoint inhibitors, which release the immune system’s brakes so it can attack cancer.
The new center will provide an integrated platform for basic and clinical research, bringing together vascular biology, immunology, and neuroscience.
A new study shows how minority patients are effectively disqualified from receiving the latest cystic fibrosis drugs approved only for people with mutations more common among white patients.
We posed the most common COVID-19 vaccine quandaries to Bryn Boslett, MD, an infectious disease expert who is leading the vaccination effort at UCSF. She explains why mRNA vaccines won’t affect your DNA, which allergies pose a risk, what 95 percent efficacy really means, and more.
In two preclinical models of COVID-19, plitidepsin showed a 100-fold reduction in viral replication in the lungs and demonstrated an ability to reduce lung inflammation.
Patients with severe COVID-19 produce antibodies that paradoxically shut down their immune system’s virus-fighting response just when they need it most.
Scientific presentations will include advances in understanding the immune response, and precision medicine-driven development of new diagnostics, therapeutics, vaccines, and population health strategies.
“It’s too soon to know if this variant will spread more rapidly than others," said Erica Pan, MD, MPH, State Epidemiologist for the California Department of Public Health.