University of California San Francisco
Give to UCSFBrowse the stories that most engaged our readers in 2019.
We asked Arnold Kriegstein, MD, PhD, director of the UCSF Developmental & Stem Cell Biology Program, about for-profit stem cell clinics and what’s real and what’s not in stem cell medicine.
International team of researchers report progress in using stem cells to develop new therapies for Pelizaeus-Merzbacher disease, a rare genetic condition affecting boys that can be fatal before 10 years of age.
The NIH has awarded grants to Faranak Fattahi, Alexander Pollen, and Vasanth Vedantham to pursue highly innovative and unusually impactful biomedical research.
Study shows that the adult-to-iPSC conversion process can mutate DNA found in mitochondria, causing mice and humans to reject iPSCs, and stem cell transplants more generally.
In a paper researchers describe a technique that uses a special version of CRISPR developed at UCSF to systematically alter the activity of genes in human neurons generated from stem cells, the first successful merger of stem cell-derived cell types and CRISPR screening technologies.
Brain damage associated with MS specifically targets a common class of brain cells called projection neurons
The Eli and Edythe Broad Foundation will be making three gifts totaling $30 million to fund innovative research, faculty recruitment, training, and retention at The Broad Foundation’s namesake stem cell research centers at UCSF, the UCLA and the USC.
A new study suggests that the human brain may maintain reserves of immature neurons throughout life, using these “Peter Pan” cells in a similar manner to the neurogenesis seen in other species
Changes in gene activity in specific brain cells are associated with the severity of autism in children and young adults with the disorder.
Newly discovered radiation-resistant stem cells are normally rare and inactive (left), but they take on a major role in muscle repair when regular stem cells are damaged by radiation (right). Credit:
UCSF scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally “invisible” to the immune system.
UCSF researchers created a chimpanzee brain “organoids” that mimic the development and organization of full-size brains.
UCSF researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes.
A growing number of researchers at UCSF and elsewhere have turned their attention to questions around why and how some people who age thrive and are more resilient than others.
From sensory processing disorder to how CRISPR is being explored to bring new treatments to patients, these are the stories that most engaged our readers in 2018.
The UCSF faculty members are among the 75 new members and 10 international members elected to the National Academy of Medicine, one of the highest honors in the fields of health and medicine.
Scientists at UCSF and Boston Children’s Hospital have developed a new technique for making mice with brains that combine the genetics of two different mouse strains.
Students who spent their summer doing laboratory and clinical research alongside BCHO doctors and CHORI scientists are presenting their research at a scientific symposium at CHORI on Friday, August 10.
Experiments using parasitic worms in the mouse gut have revealed a surprising new form of wound repair, a finding that could help scientists develop ways to enhance the body’s natural healing abilities.
A so-called “jumping gene” that researchers long considered either genetic junk or a pernicious parasite is actually a critical regulator of the first stages of embryonic development.
Each year, 300,000 infants worldwide are born with sickle cell. UCSF Benioff Children’s Hospitals are at the the leading edge of advancements to cure sickle cell disease.
UCSF researchers have safely transplanted a woman’s stem cells into her growing fetus, leading to the live birth of an infant with a normally fatal fetal condition.
UCSF scientists have shown that in the human hippocampus neurogenesis declines throughout childhood and is undetectable in adults.
UCSF received more than $593.9 million in federal funding from the National Institutes of Health in 2017 for research across multiple health-science arenas at the University.