Making Sense of Scents
In a first, UCSF scientists created a molecular-level, 3D picture of how an odor molecule activates a human odorant receptor.

University of California San Francisco
Give to UCSFIn a first, UCSF scientists created a molecular-level, 3D picture of how an odor molecule activates a human odorant receptor.
When we inhale an airborne virus, our lung cells take on the role of immune system first responders. Catera Wilder, PhD, studies the molecular details of this response and how it can go awry, causing the body to damage its own tissue and cells.
A new AI language program developed by Salesforce can learn the language of biology to create artificial proteins.
Trillions of invisible organisms make up the human microbiome. Now, medical scientists want to put these bugs to work.
Researchers have discovered a cellular uptake pathway for larger molecules that delivers cell-permeable drugs efficiently.
A $147 million grant will expand diversity among Alzheimer’s disease research participants, and involve partners from UCSF, the San Francisco VA Medical Center, and the Northern California Institute for Research and Education.
UCSF has revealed how blood vessel cells develop in the prenatal human brain, paving the way to fully understand the role of these cells in healthy brain development and disease.
UCSF Health is recruiting patients for the only FDA-approved study of the use of single port robotic technology for colorectal surgery in the United States.
For many women, breast cancer screening with a three-dimensional imaging technique called digital breast tomosynthesis (DBT) may not offer advantages over digital mammography, but for some it may reduce the chance of an advanced cancer diagnosis, according to a new JAMA study.
How David Julius and Ardem Patapoutian found the molecules in our bodies that sense heat, cold, touch, and pain – and transformed sensory neuroscience.
As a worldwide shortage of contrast dye for medical imaging continues, a new UCSF research letter in JAMA quantified strategies to safely reduce dye use in computed tomography (CT) by up to 83%. CT is the most common use for the dye.
The latest advances in cancer care and research will be showcased at the annual American Society of Clinical Oncology (ASCO) Annual Meeting, the world’s largest clinical cancer meeting.
How neuroscientists harnessed the power of artificial intelligence to give a paralyzed man back his voice.
Helen Diller Family Cancer Research BuildingExperts from UCSF Health will present new research and clinical findings at the annual San Antonio Breast Cancer Symposium, the world’s largest and most
A new prostate cancer test developed by UCSF and UCLA detects cancer cells that have spread to lymph nodes both inside and outside the pelvis.
In a new study, an artificial intelligence algorithm exceeded the performance of a widely available commercial system in nearly all examined diagnoses.
Following groundbreaking work on a “speech neuroprosthesis” that enabled a paralyzed man to communicate using his brain signals, the lab team answered public questions about brain-computer interfaces and the limitations of translating brain signals into code.
Researchers at UC San Francisco have successfully developed a “speech neuroprosthesis” that has enabled a man with severe paralysis to communicate in sentences, translating signals from his brain to the vocal tract directly into words that appear as text on a screen.
Scientists at UCSF have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases in mice.
Taking a page from computer engineers, biologists are trying their hands at programming cells – by building DNA circuits to guide their protein-making machinery and behavior.
Leading scientists share some of the tools and strategies that could help us better confront and contain future outbreaks.
The viruses that cause polio and COVID-19 mutate, but treatments for the diseases don’t. For over 20 years, UCSF and Gladstone Institutes scientist Leor Weinberger, PhD, has been thinking of ways to make vaccines work more efficiently by being adaptive, rather than static.
UCSF researchers have found a way to double doctors’ accuracy in detecting the vast majority of complex fetal heart defects in utero.
A team at UCSF, in collaboration with colleagues at Stanford University, has unearthed the regulatory DNA sequences of our archaic human ancestors in a discovery that sheds light on how we diverged from them 500,000 years ago.
A large study of brain MRI scans from 11,679 children between the ages of 9 and 10 reviewed by UC San Francisco neuroradiologists identified potentially life-threatening conditions in 1 in 500
There is a big, global problem: viruses such as HIV and COVID-19 mutate, but treatments for them don’t.
Tissue biologist Sarah Knox has long been fascinated with saliva. Just when she begins to doubt whether her singular passion will lead to real-world impact, an old family friend reaches out to her with a problem only she may be able to solve.
Patients with severe COVID-19 produce antibodies that paradoxically shut down their immune system’s virus-fighting response just when they need it most.
A team of researchers has identified for the first time the neurons that are among the first victims of Alzheimer’s disease.