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Multiple clinical trials have shown that GLP-1s are safe and effective for patients with obesity, diabetes and cardiovascular conditions. New evidence shows that the drugs may also protect against neurological diseases, like dementia, Parkinson's, and substance use disorder.
Epilepsy physicians Jon Kleen and Eddie Chang used high-resolution technology to see how cognition is disrupted in people with epilepsy and predict when it will occur. The new view points the way to being able to fend of these disruptions.
UCSF's Cherry Leung, associate professor of community health systems with the UC San Francisco School of Nursing, researches the gut-brain axis as a potential adjunct therapy for improving adolescent mental health.
Freeze-dried human platelets could be used as a "molecular tourniquet" for brain bleeds in the minutes to hours after a traumatic brain injury, according to a UCSF team led by Shibani Pati. The scientists envision stocking ambulances and EDs with the product.
UCSF research shows psychedelics like psilocybin may treat depression, Parkinson’s, and addiction, offering new hope in clinical trials.
Rajiv Sethi, MD, PhD, has been appointed chief of the UCSF Division of Orthopaedic Spine Surgery, one of the nation’s premier spine programs. He has also been named co-director of the UCSF Spine
UCSF researchers are studying how climate change fuels toxic algal blooms, partnering with global and tribal communities to monitor health risks and protect food security.
Researchers discover that the nerve cells that make us uniquely human are also uniquely vulnerable to dying during the waves of inflammation that occur in multiple sclerosis.
A new study traces the molecular pathway connecting the gut immune system to the brain during a parasitic infection, explaining how the immune system triggers a loss of appetite.
Poor sleep is associated with an increased risk for dementia, but many sleep studies have had inconsistent results. For the first time, used AI to analyze tiny electrical signals in the brain of 7,000 participants healthy participants to calculate “brain age." They find that dementia risk increases significantly when the brain age exceeds actual age.
Tau proteins play an important role in our normal brain function, mainly by helping to stabilize neurons in the brain. But in Alzheimer’s disease, tau proteins can misfold and tangle inside neurons.
A UCSF team finds a liver protein, released with exercise, that improves memory in aging and Alzheimer’s disease by repairing the brain’s blood vessels. It's the missing link between exercise and brain rejuvenation that many have been hunting for.
How we learn to predict an outcome isn’t determined by how many times a cue and reward happen together. Instead, how much time passes between rewards is also important. Understanding this process has implications for how we think about addiction, and could also point to faster AI algorithms.summary
For years, scientists have studied how the brain controls movement by asking patients to perform structured tasks while connected to multiple sensors in a lab. While these studies have provided
A study from UCSF shows a previously unknown connection between the Epstein-Barr virus, known to play a role in MS, and an understudied type of immune cell.
The hormone’s role in women’s health reaches far beyond reproduction.
Researchers found a "garbage man" enzyme that tags toxic clumps of proteins in the brain for removal, and saw a correlation with resilience against dementia.
In the last few years, progress has been made in the fight against Alzheimer’s disease with a class of therapies called anti-amyloid antibodies (anti-Aβ). These monoclonal anti-Aβs are proteins made
Matthew Growdon's study finds "prescription cascades" where drug side effects lead to unnecessary second prescriptions, causing further harm and costly hospitalizations.
Scientists have thought that when we hear language, the brain processes it the same way, whether it's familiar or foreign. A new study reveals that exposure to a language changes how certain clusters of neurons respond to the familiar sounds. From those changes, we develop the understanding of syllables, words, and syntax.
New research shows how brain networks differ in neurodiverse children who are and aren't resilient in the face of sensory overload.
New testing in maternal hyperoxia — giving extra oxygen to pregnant people — shows that prenatal interventions might yield better outcomes for babies with congenital heart disease.
UCSF researchers used AI to personalize Deep Brain Stimulation (DBS) for Parkinson's gait problems, leading to meaningful, customized improvements in walking and mobility—a major breakthrough for patients.
Neurologist Dr. Ptacek explains how "falling back" disrupts the 24-hour circadian clock, affecting mood and performance, with mitigation tips.
Martin Kampmann’s work, supported by the National Institutes of Health (NIH), maps cellular “decision points” that determine whether brain cells survive or die, laying the groundwork for treatments that intervene before irreversible brain damage occurs from dementia.
Image In the human brain, neurofilament light chain (NfL, shown in brown) is seen in brain cells and the neural wires that connect them. UCSF
