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A team of UC San Francisco and Stanford University scientists has discovered that a protein thought to be crucial for the body to develop and function correctly can be reduced by half in mice with no apparent ill effects.
In the state of Tikray in northern Ethiopia, where poverty and unemployment are rampant, very few have the fortune to go to college. But Getahun Weldeselassie nevertheless banked on education as his best shot at a better life.
Withholding angiotensin receptor blockers for longer than two days after surgery is associated with a significantly increased risk of postoperative death, according to a study of more than 30,000 patients.
After decades of challenges, scientists have developed an imaging technique that allows them to see the detailed structure of tiny proteins — and it's changing how we think about medicine.
By studying fossilized teeth from thousands of extinct rodent species, UCSF and University of Helsinki scientists have shown how fundamental evolutionary mechanisms drive the emergence of novel mammalian stem cells.
A research team led by scientists from UCSF, Baylor College of Medicine, and Texas Children’s Hospital has identified a new autoimmune syndrome characterized by a combination of severe lung disease and arthritis that currently has no therapy.
A team led by UCSF scientists has discovered a possible reason why angiogenesis inhibitors often work in the short term but usually become ineffective within months, one that could lead to a way to prevent cancer relapse.
About a quarter of all atrial fibrillation patients at the lowest risk for stroke receive unnecessary blood thinners from cardiology specialists, according to UCSF researchers.
Researchers at UCSF have pulled aside the curtain on a protein informally known as the “wasabi receptor,” revealing at near-atomic resolution structures that could be targeted with anti-inflammatory pain drugs.
For the first time, scientists have isolated beige fat in adult humans that's able to convert energy-storing white fat cells into the energy-burning kind.
UCSF scientists have identified a biological escape hatch that explains the resistance to targeted drug treatment in some lung cancer patients.
The evolution and development of structures as diverse as limbs, fingers, teeth, somites and vertebrae may have more in common than once believed, according to a new study.
A research team, led by a UCSF biologist, has isolated energy-burning “beige” fat from adult humans, which is known to be able to convert unhealthy white fat into healthy brown fat.
A new study of acute lymphoblastic leukemia led by UCSF researchers puts an intriguing new twist on anti-cancer strategies.
A new study of acute lymphoblastic leukemia has revealed that the disease has two distinct subtypes, and provides preliminary evidence that about 13 percent of cases may be successfully treated with targeted drugs.
New research finds a special protein may control the survival of deep, near-dormant cancer cells that allow tumors to regrow even after other cells have been eradicated.
A team of UCSF and high school students won "Best Presentation" at the most recent international "Genetically Engineered Machine" competition, where engineering meets biology.
Two dozen scientific papers published online simultaneously present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types.
A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study.
Researchers at UCSF have identified the chemical that signals to roundworms when they are hungry, the same chemical implicated in several neurodegenerative disorders. The finding may provide useful clues for understanding and treating these disorders.
Meet the Tetrahymena, the pear-shaped protozoa that played a starring role in Nobel Prize-winning research about aging.
With advances in technology and better understanding of people, the health sciences are constantly pushing toward more effective treatments and cures. The question is, where will we see the next breakthroughs in 2015?
UCSF is among the top universities in the world yet again, ranking among the top five in seven subject areas, according to the inaugural U.S. News & World Report Best Global Universities report.
The application of a new, precise way to turn genes on and off within cells is likely to lead to a better understanding of diseases and possibly to new therapies, according to UCSF scientists.
Bacteria that normally live in and upon us have genetic blueprints that enable them to make thousands of molecules that act like drugs, and some of these molecules might serve as the basis for new human therapeutics, according to UCSF researchers.
Peter Walter has won the 2014 Lasker Award, popularly known as the "American Nobels." It’s the second major accolade this year alone for the Germany native, whose career didn't always point toward being a research scientist.
Peter Walter, PhD, professor of biochemistry and biophysics at UCSF, has received the 2014 Lasker Basic Medical Research Award.
New research partly led by UCSF-affiliated scientists suggests that one in 10 cancer patients would be more accurately diagnosed if their tumors were defined by cellular and molecular criteria rather than by the tissues in which they originated.
A new study is the first to show that while the impact of life’s stressors accumulate over time and accelerate cellular aging, these negative effects may be reduced by maintaining a healthy diet, exercising and sleeping well.