Navigating From the Genome to the Clinic Using ‘Cell Maps’
Nevan Krogan, PhD, director of UCSF’s Quantitative Biosciences Institute, examines in detail the effects of a handful of genes that seem to play an outsize role in a wide array of diseases.
University of California San Francisco
Give to UCSFNevan Krogan, PhD, director of UCSF’s Quantitative Biosciences Institute, examines in detail the effects of a handful of genes that seem to play an outsize role in a wide array of diseases.
For 29 years, Rashetta Higgins was wracked by epileptic seizures. UCSF neurologists used a pioneering imaging technique to spot what was triggering them and then removed that region from her brain. Now Rashetta is living a seizure-free life.
Wei Gordon was among nine finalists in the sixth annual UCSF Grad Slam, held March 31 – after a two-year hiatus due to the pandemic – competing to inform and entertain with three-minute talks based on their own research.
Brain tumor patients survived longer when treated aggressively with surgery, radiation and chemotherapy. Now, a UCSF study underscores the critical role of genomic profiling in diagnosing and grading brain tumors.
Skin diseases both common and rare can be better diagnosed and treated using genetic fingerprinting based on knowledge gained through a new UCSF study, according to researchers who developed new approaches for using the latest techniques to analyze gene activity in cells obtained from affected skin.
Not everyone needs 8 hours of sleep, say UCSF researchers. Some lucky people are “elite sleepers,” packing sleep’s benefits into 4 to 6 hours a night. Their genes may hold clues to how efficient sleep can fend off dementia.
UCSF researchers successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about one in four cancer deaths.
Using AI in ECG analysis improves diagnosis, treatment and monitoring of hypertrophic cardiomyopathy, a leading cause of sudden death in adolescents.
A new fast-track review for UCSF gene therapy could help more kids with deadly Artemis-SCID disease get life-saving treatment sooner.
Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types.
A UCSF-led study found a new drug for ALS that shows to slow or temporarily stall the progression of ALS in a select group of patients, with three times as many patients' disease slowing compared to those who received a placebo.
A new “atlas” of every cell in the brain’s blood vessels reveals that some strokes are caused by immune cells interacting with arteries, in a new study by UCSF researchers.
For years, physicians have been taught to prescribe different drugs to Black people with high blood pressure. A recent UCSF study calls that into question.
UCSF researchers found that cancers from different parts of the body are immunologically similar to one another. They described 12 classes of "immune archetypes" to classify cancer tumors, which can provide unique strategies for enhancing patients’ choice of cancer immunotherapies.
A natural language processing study parses doctor-patient communication at an unprecedented scale and offers new ways to help doctors communicate with their patients.
Keith Yamamoto, PhD, UCSF’s director of precision medicine, explains how a new tool – a knowledge network – will transform health care.
A recent UCSF study tested possible triggers of a common heart condition, including caffeine, sleep deprivation and sleeping on the left side, and found that only alcohol use was consistently associated with more episodes of heart arrhythmia.
A man was paralyzed from the neck down in a surfing accident. Now he can walk again. Using machine learning, UCSF researchers found that controlling blood pressure during surgery may aid in patient recovery from spinal cord injuries.
A UCSF and Stanford study of electronic health records linked SSRIs, the most widely prescribed antidepressants, to survival for COVID-19 patients.
The new Weill Neurosciences Building, designed to foster connections among scientists and clinicians in neurology, neurosurgery and psychiatry, will serve as a global destination for researchers to develop innovative treatments for intractable brain diseases.
UCSF’s research has been ranked among the top in the world, according to the latest U.S. News & World Report’s Best Global Universities 2022 rankings.
A groundbreaking national study led by UCSF finds that treating anal cancer precursor lesions reduces cancer risk for people with HIV.
Two new studies of the developing human brain are helping researchers reconcile a long-held debate over how the brain forms.
UCSF Health physicians have successfully treated a patient with severe depression by tapping into the specific brain circuit involved in depressive brain patterns and resetting them using the equivalent of a pacemaker for the brain.
A new prostate cancer test developed by UCSF and UCLA detects cancer cells that have spread to lymph nodes both inside and outside the pelvis.
In a new study, an artificial intelligence algorithm exceeded the performance of a widely available commercial system in nearly all examined diagnoses.