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Immune-Cell Population Predicts Immunotherapy Response in Melanoma

The abundance of a subtype of white blood cells in melanoma tumors can predict whether or not patients will respond to a form of cancer immunotherapy known as checkpoint blockade, according to a new study led by UCSF researchers and physicians.

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Gut Bacteria Linked to Rare Autoimmune Disease

A new study led by UCSF scientists shows that a bacterium commonly found in the human gut is overrepresented in patients with a rare, often disabling autoimmune disease known as neuromyelitis optica.

Researchers Map Zika’s Routes to the Developing Fetus

Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UCSF and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus.

Covert Inflammation May Trigger Many Forms of Cancer

A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer – even when patients don’t display typical signs of inflammation.

UCSF Researchers Reappraise Treatment for Belly Birth Defect

UC San Francisco researchers have shed light on how the immune system of a fetus can run amok, triggering inflammation in the developing intestines that protrude outside of the body through a hole beside the belly button.

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Wrapping Up Multiple Sclerosis

With one drug to shut down its progression and another to undo its damage, plus a worldwide effort stalking the origins of multiple sclerosis, MS doesn’t stand a chance.

Dr. Stephen Hauser, examining a patient, gestures for her to look straight ahead.

UCSF Immunologist to Head New Parker Institute for Cancer Immunotherapy

Renowned UCSF immunologist Jeffrey Bluestone, PhD, has been named president and CEO of the Parker Institute for Cancer Immunotherapy, a national initiative launched with a $250 million grant from The Parker Foundation, established by Silicon Valley entrepreneur Sean Parker.

UCSF Research Suggests New Model for Cancer Metastasis

Scientists at UC San Francisco have been able to directly observe, for the first time, how invasive cancer cells create a beachhead as they migrate to the lung in a mouse model of metastatic cancer.