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Scientists have identified a gene underlying a disease that causes temporary paralysis of skeletal muscle. The finding, they say, illustrates how investigations of rare genetic diseases can drive insights into more common ones.
UCSF studies of frontotemporal dementia may shed light on Thanksgiving and year-round overeating.
UCSF’s Program for Breakthrough Biomedical Research, which finances creative, risky projects that have the potential to transform their fields, has had an impressive track record.
Molecular biologist Elizabeth H. Blackburn, PhD, 60, of the University of California, San Francisco, received the 2009 Nobel Prize in Physiology or Medicine on December 10th, 2009 in Stockholm, Sweden.
Telomeres — which are the DNA repeats that form the tips of chromosomes and are produced by the telomerase enzyme — play a crucial, and curious, role in the life of the cell.
UCSF researchers have developed a new approach to identify specific genes that influence how cancer cells respond to drugs and how they become resistant. This strategy, which involves producing diverse genetic mutations that result in leukemia and associating specific mutations with treatment outcomes, will enable researchers to better understand how drug resistance occurs in leukemia and other cancers, and has important long-term implications for the development of more effective therapies.
Tiny, solitary spikes that stick out of nearly every cell in the body play a central role in a type of skin cancer, new research has found. The discovery in mice shows that the microscopic structures known as primary cilia can either suppress or promote this skin cancer, depending on the mutation triggering the disease.
Scientists have discovered the first gene involved in regulating the optimal length of human sleep, offering a window into a key aspect of slumber, an enigmatic phenomenon that is critical to human physical and mental health
UCSF has received a five-year grant to establish a multi-campus center where researchers will study how stress and socioeconomic status influence weight.
Older veterans with post-traumatic stress disorder were almost twice as likely to develop dementia as veterans without PTSD in a study of more than 180,000 veterans led by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.
UCSF researchers have discovered inherited DNA that increases risk for the most deadly brain cancers.
Sugar is a poison, says Robert Lustig, MD, UCSF obesity expert and pediatric endocrinologist.
Scientists have long thought that processes occurring during sleep were responsible for cementing the salient experiences of the day into long-term memories. Now, however, a study of scampering rats suggests that the mechanisms at work during sleep are also active while the animals are awake -- and that they encode events more accurately.
Narcolepsy, a sleep disorder that can cause sufferers to suddenly lose muscle tone and start dreaming, is an autoimmune disease, a team led by UCSF and Stanford scientists finds.