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Math Points to 100-Times Faster Mapping of Gene Activity

New research by UCSF scientists could accelerate – by 10 to 100-fold – the pace of many efforts to profile gene activity, ranging from basic research into how to build new tissues from stem cells to clinical efforts to detect cancer or auto-immune diseases by profiling single cells in a tiny drop of blood.

Wrapping Up Multiple Sclerosis

With one drug to shut down its progression and another to undo its damage, plus a worldwide effort stalking the origins of multiple sclerosis, MS doesn’t stand a chance.

Dr. Stephen Hauser, examining a patient, gestures for her to look straight ahead.

Cytokine Triggers Immune Response at Expense of Blood Renewal

Stem cell biologists at UCSF have demonstrated that IL-1 itself directly transforms the blood system by driving blood stem cells in the bone marrow to switch away from their restorative, rejuvenating role in blood renewal and towards emergency production of immune cells.

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Malaria-Free World Possible Within a Generation, Study Says

Global malaria eradication is possible within a generation, but only with renewed focus, new tools and sufficient financial support, according to a paper published in The Lancet by the Global Health Group’s Malaria Elimination Initiative at UCSF.

Brain’s Immune System May Trigger Frontotemporal Dementia

Frontotemporal dementia, the second most common cause of dementia in people under 65, may be triggered by a defect in immune cells called microglia that causes them to consume the brain’s synaptic connections, according to new research led by UCSF scientists.

Scientists ID Gene Behind Rare Childhood Syndrome

In a study of 10 children published online in the American Journal of Human Genetics on April 14, the researchers linked a constellation of birth defects affecting the brain, eye, ear, heart and kidney to mutations in a single gene, called RERE.

UCSF Immunologist to Head New Parker Institute for Cancer Immunotherapy

Renowned UCSF immunologist Jeffrey Bluestone, PhD, has been named president and CEO of the Parker Institute for Cancer Immunotherapy, a national initiative launched with a $250 million grant from The Parker Foundation, established by Silicon Valley entrepreneur Sean Parker.