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T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.
A new "subway map" of immune networks connects gene variation to risk for autoimmune disease.
A new UCSF study reveals how gut inflammation can disrupt not only the digestive system, but also the skin. It’s a tale in which the main players are specialized immune cells and the bacterial communities — called microbiomes — that dwell within the gut and skin.
Seth Blumberg, MD, PhD, an assistant professor of medicine, is clinical specialist in infectious disease, including Monkeypox. He offers insight in the recent outbreak in a Q&A.
For the new study published in the journal Nature on March 30, 2022, researchers at Gladstone Institutes, the Salk Institute for Biological Studies, and UC San Francisco (UCSF) teamed up. Their findings, shed light on how obesity can change the immune system and, potentially, how clinicians might be able to better treat allergies and asthma in obese people.
