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Sowing Stem Cells

Organoids serve as dioramas of disease, allowing UCSF scientists to understand how and why problems occur during tissue development. It's also a small step toward the creation of full-sized organs we could use for transplant.

Sculptures of three human teeth made out of flowers and moss.

Mouse Teeth Providing New Insights into Tissue Regeneration

UCSF researchers are looking to the front teeth of mice to to help understand how stem cells know when it’s time for them to expand in numbers and transform into mature, adult cells in order to renew injured or aging tissue.

Science in Focus: Rebuilding the Salivary Gland After Radiation

UCSF researchers are working to figure out how mouse stem cells divide and differentiate into acinar cells to rebuild the salivary gland after an injury. Such research could apply to patients who often lose the ability to produce saliva after undergoing radiation therapy for head and neck cancers.