Navigating From the Genome to the Clinic Using ‘Cell Maps’
Nevan Krogan, PhD, director of UCSF’s Quantitative Biosciences Institute, examines in detail the effects of a handful of genes that seem to play an outsize role in a wide array of diseases.
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Discovering a Seizure-Free Life with Help from 3-D ‘Heat Map’ Technology
For 29 years, Rashetta Higgins was wracked by epileptic seizures. UCSF neurologists used a pioneering imaging technique to spot what was triggering them and then removed that region from her brain. Now Rashetta is living a seizure-free life.
Talk on the Secrets of Fruit-Eating Mammals Wins 2022 UCSF Grad Slam
Wei Gordon was among nine finalists in the sixth annual UCSF Grad Slam, held March 31 – after a two-year hiatus due to the pandemic – competing to inform and entertain with three-minute talks based on their own research.
Genomic Sequencing Is Changing Diagnosis, Treatment for Patients with Brain Cancer
Brain tumor patients survived longer when treated aggressively with surgery, radiation and chemotherapy. Now, a UCSF study underscores the critical role of genomic profiling in diagnosing and grading brain tumors.
Molecular Profiling Advances Diagnosis, Treatment of Skin Diseases
Skin diseases both common and rare can be better diagnosed and treated using genetic fingerprinting based on knowledge gained through a new UCSF study, according to researchers who developed new approaches for using the latest techniques to analyze gene activity in cells obtained from affected skin.
When It Comes to Sleep, It’s Quality Over Quantity
Not everyone needs 8 hours of sleep, say UCSF researchers. Some lucky people are “elite sleepers,” packing sleep’s benefits into 4 to 6 hours a night. Their genes may hold clues to how efficient sleep can fend off dementia.
Treating Tough Tumors by Exploiting Their Iron ‘Addiction’
UCSF researchers successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about one in four cancer deaths.
Using AI in Electrocardiogram Analysis Can Improve Diagnosis and Treatment of Hypertrophic Cardiomyopathy
Using AI in ECG analysis improves diagnosis, treatment and monitoring of hypertrophic cardiomyopathy, a leading cause of sudden death in adolescents.
UCSF Gene Therapy for Deadly Mutation Fast-Tracked for FDA Review
A new fast-track review for UCSF gene therapy could help more kids with deadly Artemis-SCID disease get life-saving treatment sooner.
Immune Cells Leave Fingerprints on Tumors Metastasized to the Brain, Offering Clues to Future Therapies
Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types.
Drug Offers New Hope to Select Patients with ALS, UCSF-CPMC Study Shows
A UCSF-led study found a new drug for ALS that shows to slow or temporarily stall the progression of ALS in a select group of patients, with three times as many patients' disease slowing compared to those who received a placebo.
Newly Discovered Immune Cells Play a Role in Hemorrhagic Stroke
A new “atlas” of every cell in the brain’s blood vessels reveals that some strokes are caused by immune cells interacting with arteries, in a new study by UCSF researchers.
Race-Based Prescribing for Black People with High Blood Pressure Shows No Benefit
For years, physicians have been taught to prescribe different drugs to Black people with high blood pressure. A recent UCSF study calls that into question.
Sorting Cancers by ‘Immune Archetypes’ May Offer New Approach For Precision Immunotherapies
UCSF researchers found that cancers from different parts of the body are immunologically similar to one another. They described 12 classes of "immune archetypes" to classify cancer tumors, which can provide unique strategies for enhancing patients’ choice of cancer immunotherapies.
