New research by UCSF stem cell biologists has revealed that a DNA-binding protein called Foxd3 acts like a genetic traffic signal, holding that ball of undifferentiated cells in a state of readiness for its great transformation in the third week of development.
We asked experts across UCSF to identify what's ahead in how we approach research, what disease areas will see major advances, and where basic science will be translating into real treatments.
Researchers at UCSF have succeeded in mapping the genetic signature of a unique group of stem cells in the human brain that seem to generate most of the neurons in our massive cerebral cortex.
UCSF scientists describe capturing and studying individual metastatic cells from human breast cancer tumors implanted into mice as the cells escaped into the blood stream and began to form tumors elsewhere in the body.
Zev Gartner is working to building a fully functioning 3-D human breast tissue that will allow him to test potential cancer therapies, an innovation that's earned him a spot among Popular Science's "Brilliant 10" this year.
UCSF researchers have successfully isolated human muscle stem cells and shown that the cells could robustly replicate and repair damaged muscles when grafted onto an injured site.
Emmanuelle Passegué’s passion for blood is focused on rejuvenation and longer life. This may sound like something out of a vampire story, but her work is rooted in a different kind of mystery: one that could hold the key to how well we age and respond to diseases.
UCSF researchers have for the first time developed a method to precisely control embryonic stem cell differentiation with beams of light, enabling them to be transformed into neurons in response to a precise external cue.
Researchers Gail Martin and Allan Balmain are UCSF's newest members of the Royal Society.