Organoids serve as dioramas of disease, allowing UCSF scientists to understand how and why problems occur during tissue development. It's also a small step toward the creation of full-sized organs we could use for transplant.
UCSF researchers are looking to the front teeth of mice to to help understand how stem cells know when it’s time for them to expand in numbers and transform into mature, adult cells in order to renew injured or aging tissue.
Studying brain disorders is complicated for many reasons, not the least being the ethics of obtaining living neurons. To overcome that obstacle, UCSF postdoc Aditi Deshpande is starting with skin cells.