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If Anti-Seizure Meds Don’t Work for Epilepsy, Can Surgery Help?
Vikram Rao, director of the UCSF Epilepsy Center, discusses why a third of seizure patients don’t respond to medication and the promising new surgical and technological treatments available.
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These Cells Have Hidden Powers That Could Heal Brain Injuries
UCSF scientists discovered that an overlooked cell type in the brain plays a central role in healing traumatic brain injury. Understanding how it does this will lead to treatments for injuries that currently have only minimal interventions.
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Scientists Look to Commercial Dyes to Help them Diagnose Dementia
A study screened dyes found in textiles and in the laser industry that can be used in imaging for preclinical studies to diagnose and differentiate between neurodegenerative diseases. Currently, dyes used in mouse studies cannot distinguish between different types of dementia.
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Bruce Willis’ Personality Changes Key to Dementia Diagnosis: UCSF Expert
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From Chronic Pain to Parkinson’s, 4 Ways DBS is Changing Care
UCSF looks back on four ways it pioneered deep brain stimulation with the help of federal funding, helping patients with Parkinson’s Disease, chronic pain, depression, and more.
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This Protein Slows the Aging Brain, and We Know How to Counter It
Scientists discover a protein that gets concentrated in the brain during aging, leading brain connections to wither and cognitive decline to accelerate - and a way to counter its effects.
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Treating Chronic Pain is Hard. An Experimental Approach Shows Promise.
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Two UCSF Researchers Are Named Pew Latin American Fellows
Two new Pew Latin American fellows, Beatriz De Moraes, PhD, and Lilian Gomes de Oliveira, PhD, will each receive a $30,000 annual stipend for two years to support their work at the crossroads of immunology and neuroscience.
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Composer Reimagines His Harvey Milk Opera While Rebuilding Life After Traumatic Injury
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Meet the Little Brain Region that Helps You Say What’s on Your Mind
Researchers discovered that a different part of the brain handles stringing sounds and words together into coherent sentences. The information could help people who have had strokes and lost the ability to create sentences.
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These Immune Cells Eat Molecular Trash to Keep Alzheimer’s at Bay
Microglia, a type of brain immune cell, can gobble up amyloid beta protein, which clumps together into toxic aggregates during Alzheimer's disease.
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Do These Two Cancer Drugs Have What It Takes to Beat Alzheimer’s?
Scientists at UCSF and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer’s, potentially slowing or even reversing its symptoms.
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Tailored Deep Brain Stimulation Improves Walking in Parkinson’s
For patients with Parkinson's disease, changes in their ability to walk can be dramatic. “Parkinson’s gait,” as it is often called, can include changes in step length and asymmetry between legs. This
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A CRISPR Approach to Neurodegenerative Diseases
The Byers Award recognizes outstanding research by faculty members in the middle of their careers. Martin Kampman’s honorary 2025 lecture is titled “A CRISPR approach to neurodegenerative diseases.”
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Visual Migraine Symptoms Linked to Tiny Brain Lesions
Visual auras, like those that occur in migraines, may be signs of small injuries to the brain’s visual cortex, according to a clinical trial at UC San Francisco that tracked the appearance of these
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Why Do Some Brain Regions Resist Alzheimer’s?
It’s been recognized for some time that Alzheimer’s disease affects brain regions differently and that tau — a protein known to misbehave — plays an important role in the disease. Normally, tau helps
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Can Music Benefit Our Brains?
An expert in cognitive neuroscience shares the ways that music may help flex our neurons, plus her top tips for a music-filled life.
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Why Is Discovery Research So Important?
Neuroscientist Grae Davis, PhD, unpacks why public understanding of science matters.
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He Discovered What Drives MS
The Oscar of science: Stephen Hauser’s dogged determination to defeat multiple sclerosis has earned him a Breakthrough Prize, one of science’s top honors.
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Can We Train Our Brain to Unlearn Chronic Pain?
Scientists are working to rewire the brain’s pain pathways and unlock lasting relief.
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How Serious is Your Brain Injury? New Criteria Will Reveal More
After more than 50 years, the assessment of traumatic brain injuries gets an overhaul. Clinicians say the proposed framework will lead to more accurate diagnoses and treatment, providing more rigorous care for some patients and preventing premature discussions about halting life support in others.
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3 UCSF Scientists Are Elected to the National Academy of Sciences
Neurosurgeon Edward Chang, MD, developmental geneticist Thomas Kornberg, PhD, and virologist Raul Andino-Pavlovsky, PhD, have been elected to the National Academy of Sciences (NAS), one of the highest honors in American science.
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Breakthrough Multiple Sclerosis Therapy by UCSF Doctor Transforms Treatment for Millions
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Bay Area Patients Among First in U.S. To Receive Life-Changing Parkinson’s Treatment
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Stephen Hauser Wins Breakthrough Prize for Role in Redefining MS
Neuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences.
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How Your Immune System Plays Matchmaker to Find and Kill HIV
Ten UCSF graduate students presented their research in accessible, 3-minute talks at the 2025 Grad Slam event. This year’s first-place talk was by Sophia Miliotis on how our immune system uses matchmaking skills to look for signs of viruses in cells that should be destroyed.
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How Your Brain Manages Cholesterol Could Increase Alzheimer’s Risk
Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.
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Lo-Res to Hi-Res, A Better way to Pinpoint Where Seizures Begin
Locating seizure onset zones is a critical requirement for epilepsy surgery. This often relies upon intracranial recordings, but finding the exact zone can still present challenges. An experimental study capturing seizures on grid electrode arrays of varying density found that higher density grid arrays produced more specificity in seizure onset areas.
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NIH Funding Drives UCSF’s Pursuit of Better Health for All
UCSF received $815 million in awards from the National Institutes of Health (NIH) last year for research that will improve the lives of patients in the U.S. and around the world.
