First Clear-Cut Risk Genes for Tourette Disorder Revealed
Researchers made a significant advance, identifying the first “high-confidence” risk gene for Tourette disorder as well as three other probable risk genes.
University of California San Francisco
Give to UCSFResearchers made a significant advance, identifying the first “high-confidence” risk gene for Tourette disorder as well as three other probable risk genes.
After undergoing surgery, elderly patients often experience cloudy thinking. Mounting evidence suggests that heightened inflammation in the brain following surgery is the more likely cause.
A newly approved drug that is the first to reflect the current scientific understanding of multiple sclerosis is holding new hope for the hundreds of thousands Americans living with the disease. It also highlights the importance of clinician scientists like UCSF’s Stephen Hauser who are working to transform research into cures for patients.
Neuroimaging is helping to distinguish between depression and dementia – two diseases with overlapping symptoms that can be difficult to diagnose properly.
Studying brain disorders is complicated for many reasons, not the least being the ethics of obtaining living neurons. To overcome that obstacle, UCSF postdoc Aditi Deshpande is starting with skin cells.
Sharks, rays and skates can hunt for prey hidden in the sandy sea floor by “listening” for faint traces of bioelectricity – they can literally sense their prey’s heart beating.
In an unprecedented leap from lab to patients, a potential treatment for childhood epilepsy identified in experiments with zebrafish.
New research is paving the way to a precision medicine approach to the diagnosis and treatment of patients with traumatic brain injury.
Research uses brain “organoids” — tiny 3D models of human organs that scientists grow in a dish to study disease — to identify root causes of MDS, a rare genetic disorder that causes fatal brain malformations.
Poor performance on a simple odor identification test was associated with a significantly increased risk of developing dementia years later.
Distinct sets of genetic defects in a single neuronal protein can lead either to infantile epilepsy or to autism spectrum disorders.
A common treatment for irregular heartbeats known as catheter ablation may result in the formation of brain lesions when it is performed on the left side of the heart.
For concussion sufferers, physicians may now be able to predict early on who is more likely to continue experiencing symptoms months or years after the head-jarring event.
UC San Francisco and Pfizer Inc.’s Centers for Therapeutic Innovation have renewed an agreement to identify and develop biologic compounds against both known and novel targets.
Researchers at UCSF have developed a new optogenetic tool that can be used to completely eliminate single cells from brain networks in animals. The researchers believe the new tool will enable exquisitely precise experiments to help researchers understand how each cell contributes to the whole.
In findings that show the effectiveness of a new strategy for treating multiple sclerosis, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab in both relapsing multiple sclerosis and primary progressive multiple sclerosis.
UCSF scientists have discovered an unexpected mechanism the brain uses to seamlessly compensate when speech sounds are obscured by noise.
Stories about sensory processing disorder, videos about “zombie” cancer cells, and news about the effects of caffeine and alcohol on the heart were among the topics that most engaged our readers in 2016.
A shared biological mechanism may drive the progression of both Alzheimer’s disease and chronic traumatic encephalopathy, a neurodegenerative condition associated with repeated concussions and brain trauma.
UCSF researchers identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin can prevent the virus from infecting these cells.
UCSF researchers have received $1.2 million for their work to make imaging machines smarter, so they can detect neurological emergencies and triage patients for immediate treatment.
Next-generation sequencing for patients at UCSF Medical Center is prompting changes in brain tumor diagnoses for some children and a retooling of treatment plans in many cases.
UCSF has ranked as one of the top 20 universities in the world, according to the 2017 Best Global Universities rankings released Tuesday by U.S. News & World Report.
Research led by UCSF scientists has revealed that mutations in a gene linked with brain development may dispose people to multiple forms of psychiatric disease by changing the way brain cells communicate.
Researchers at UCSF have discovered a previously unknown mass migration of inhibitory neurons into the brain’s frontal cortex during the first few months after birth.
Using a mouse model of multiple sclerosis, UCSF scientists demonstrated that regenerating myelin can both protect neurons from damage and restore lost function.
Major childhood psychological and social stressors, increase the odds of shorter telomere length in adulthood, according to a study led by researchers at UC San Francisco.
Chronic pain and loss of bladder control are among the most devastating consequences of spinal cord injury.
A digital assessment platform designed to look and feel like a video game may successfully flag children with attention disorders.