An Estrogen Receptor that Promotes Cancer also Causes Drug Resistance
Researchers at UCSF have gained insight into how cancer cells proliferate despite a myriad of stresses.
University of California San Francisco
Give to UCSFResearchers at UCSF have gained insight into how cancer cells proliferate despite a myriad of stresses.
Individuals who contract COVID-19 while pregnant face a higher risk of having a very preterm birth, as well as any preterm birth.
A team of researchers at have uncovered some intriguing clues in the mystery of how some poison birds and frogs evade their own toxins.
Working in mice, UCSF researchers have found that a recently discovered subset of cells in the immune system may prevent the mother’s immune system from attacking the placenta and fetus.
Messenger RNA vaccines against COVID-19 were not detected in human milk, according to a small study by UCSF, providing early evidence that the vaccine mRNA is not transferred to the infant.
Taking a page from computer engineers, biologists are trying their hands at programming cells – by building DNA circuits to guide their protein-making machinery and behavior.
Plenty of probiotic yogurts, pickles and kombuchas claim to boost our digestive health with armies of microbes, but some scientists have more ambitious therapeutic plans for the “bugs” that colonize us. They hope to leverage these microbes as living therapeutics for a range of health conditions, including ulcerative colitis, multiple sclerosis, eczema and asthma.
T cells – immune cells that patrol our bodies in search of trouble – have become a central focus for UC San Francisco scientists working on living cell therapies, an approach that views cells
The B.1.1.7 coronavirus variant—also known as Alpha—may be more infectious because it contains mutations that make it better adapted to foil the innate immune system, at least for long enough to allow the virus to replicate and potentially find new hosts, according to a new study.
For older adults, participating in social activities can protect against physical and mental signs of aging, but it may also pose risks, especially for women. A new analysis of national data led by
An elderly man had symptoms no one could explain – until Amy Berger, MD, PhD, and her team investigated.
Hidden autoimmunity may explain how the coronavirus wreaks such widespread and unpredictable harm.
The viruses that cause polio and COVID-19 mutate, but treatments for the diseases don’t. For over 20 years, UCSF and Gladstone Institutes scientist Leor Weinberger, PhD, has been thinking of ways to make vaccines work more efficiently by being adaptive, rather than static.
Scientists now have shown that the weakening of an astronaut’s immune system during space travel is likely due in part to abnormal activation of immune cells called T regulator cells.
Sophie Dumont, winner of the 2021 Byers Award for Basic Science, focuses on finding out how, as well whether therapeutic targets exist to ensure equal – and healthy – division of chromosomes.
What kills most people who die from cancer is not the initial tumor. It’s the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to different organs.
UCSF researchers have figured out precisely what receptor tyrosine kinases are, how they form and their role in cancer.
Scientists at UCSF are learning how immune cells naturally clear the body of defunct – or senescent – cells that contribute to aging and many chronic diseases
Loneliness and social isolation have been significant problems for the general population during the COVID-19 pandemic, but for cancer patients these issues were particularly acute, likely due to isolation and social distancing, according to a new UCSF study.
Researchers at UCSF have demonstrated how to engineer smart immune cells that are effective against solid tumors, opening the door to treating a variety of cancers that have long been untouchable with immunotherapies.
A new study suggests that the dangers posed by wildfire smoke may also extend to the largest organ in the human body, and our first line of defense against outside threat: the skin.
The study is the first comprehensive review of fatalities linked to the deadly chemical in the United States and identified more deaths than previously reported.
Scientists have figured out how to modify CRISPR’s basic architecture to extend its reach beyond the genome and into what’s known as the epigenome.
Cancer starts with mutations in a cell’s DNA, but new UCSF research shows that the endurance of a tumor relies on its ability to rapidly evolve and adapt to challenges brought about by the environment in which it grows.
For some people a sales ban that takes the temptation out of the workplace may not be enough.
Scientists at UCSf have detected 109 chemicals in a study of pregnant women, including 55 chemicals never before reported in people and 42 “mystery chemicals,” whose sources and uses are unknown.