University of California San Francisco
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An algorithm developed by scientists at UC San Francisco and UC Berkeley did better than two out of four expert radiologists at finding tiny brain hemorrhages in head scans—an advance that one day may help doctors treat patients with TBI, strokes and aneurysms.
Research team has detected the immunological remnants of a common seasonal virus in spinal fluid from dozens of patients diagnosed with acute flaccid myelitis (AFM). The findings provide the clearest evidence to date that AFM is caused by an enterovirus (EV) that invades and impairs the central nervous system.
UCSF scientists have caught brain circuits in the act of rewiring themselves to change how they respond to sensory input.
The UCSF scientists who identified the two known human genes that promote “natural short sleep” have now discovered a third, and it’s also the first gene that’s ever been shown to prevent the memory deficits that normally accompany sleep deprivation.
The National Institutes of Health has awarded a five-year, multi-investigator research grant expected to total more than $63 million to Mayo Clinic and UC San Francisco, to advance treatments for frontotemporal lobar degeneration.
Scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia, adding to growing evidence that the loss of brain cells associated with dementia spreads via the synaptic connections between established brain networks.
Distinct patterns of electrical activity in the sleeping brain may influence whether we remember or forget what we learned the previous day.
International team of researchers report progress in using stem cells to develop new therapies for Pelizaeus-Merzbacher disease, a rare genetic condition affecting boys that can be fatal before 10 years of age.
UCSF study conducted in songbirds shows that what at first appear to be genetic constraints on birds’ song learning abilities could be largely eliminated by tailoring instruction to better match the birds’ inborn predispositions.
UCSF scientists who identified the only human gene known to promote “natural short sleep” have discovered a second.
Blood test that is currently under development may flag concussion in CT-negative patients, enabling them to be evaluated for long-term complications.
Researchers discovered a scorpion toxin that targets the “wasabi receptor,” which they think it can be used as a tool for studying chronic pain and inflammation, and may eventually lead to the development of new kinds of non-opioid pain relievers.
In a paper researchers describe a technique that uses a special version of CRISPR developed at UCSF to systematically alter the activity of genes in human neurons generated from stem cells, the first successful merger of stem cell-derived cell types and CRISPR screening technologies.
Scientists identify faulty molecular recycling as potential driver of Alzheimer’s disease.
UCSF scientists show that Alzheimer’s disease directly attacks brain regions responsible for wakefulness during the day.
UCSF scientists have for the first time decoded spoken words and phrases in real time from the brain signals that control speech.
Since 2017, UCSF researchers Winston Chiong and Eddie Chang have led a collaborative neuroethics research project funded by the NIH.
Brain damage associated with MS specifically targets a common class of brain cells called projection neurons
The Susan and Bill Oberndorf Foundation has made a new commitment of $25 million to UCSF psychiatry and the neurosciences, bringing its total giving to "UCSF: The Campaign" to $50 million.
Using advanced technology, scientists have discovered an autoimmune disease that appears to affect men with testicular cancer.
Today, our understanding of glioma subtypes has expanded to include the molecular and genetic variants that can influence a tumor’s development, prognosis, and response to treatment.
A new study suggests that the human brain may maintain reserves of immature neurons throughout life, using these “Peter Pan” cells in a similar manner to the neurogenesis seen in other species
Unlike other gene mutations linked to autism, which are thought to alter brain development before birth, the newly identified changes in brain signaling may occur closer to the onset of autism symptoms in the first years of life.