Struggling to Learn a New Language? Blame It on Your Stable Brain
A study in patients with epilepsy is helping researchers understand how the brain manages the task of learning a new language while retaining our mother tongue.
University of California San Francisco
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Q&A: Building a Speech Prosthetic for a Paralyzed Man
Following groundbreaking work on a “speech neuroprosthesis” that enabled a paralyzed man to communicate using his brain signals, the lab team answered public questions about brain-computer interfaces and the limitations of translating brain signals into code.
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Poison Frogs, Birds, Hold Clues to Antidotes for Deadly Toxins
A team of researchers at have uncovered some intriguing clues in the mystery of how some poison birds and frogs evade their own toxins.
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Dual-Drug Therapy Shows Promise for Treating Alcohol Use Disorder
UCSF researchers have leveraged two new molecules, one of which is currently in clinical oncology trials, to devise a dual-drug therapy for alcohol use disorder (AUD), without the side effects or complications associated with current treatment regimens.
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Tapping Into the Brain to Help a Paralyzed Man Speak
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“Neuroprosthesis” Restores Words to Man with Paralysis
Researchers at UC San Francisco have successfully developed a “speech neuroprosthesis” that has enabled a man with severe paralysis to communicate in sentences, translating signals from his brain to the vocal tract directly into words that appear as text on a screen.
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Gene Therapy Offers Long-Awaited Hope for Children with Rare, Incurable Disorder
Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children’s Hospitals.
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Next-Generation T-Cell Therapeutics Set Sights on Cancers, Autoimmune Disorders and More
T cells – immune cells that patrol our bodies in search of trouble – have become a central focus for UC San Francisco scientists working on living cell therapies, an approach that views cells
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Why Can’t I Sleep?
Insomnia is miserable, and lost sleep can harm our health. Now, researchers are seeing the promise of solutions in our genes.
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The Best Treatment for Insomnia Usually Isn’t a Pill
Cognitive behaviorial therapy for insomnia, the gold-standard intervention, also suggests benefits for well-being.
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Your Immune System Could Turn COVID-19 Deadly
Hidden autoimmunity may explain how the coronavirus wreaks such widespread and unpredictable harm.
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To Prevent Delirium, Increase Mobility, Connection and Sleep
UCSF researchers wanted to see if simple tweaks, like avoiding nighttime interruptions to promote sleep, nixing certain prescription drugs, and promoting exercise and social engagement, could decrease delirium in hospitalized older adults.
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Space Travel Weakens Our Immune Systems – Now Scientists May Know Why
Scientists now have shown that the weakening of an astronaut’s immune system during space travel is likely due in part to abnormal activation of immune cells called T regulator cells.
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The Eyes Offer a Window into Alzheimer’s Disease
New research by UCSF scientists shows retinal scans can detect key changes in blood vessels that may provide an early sign of Alzheimer’s disease.
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Researchers Observe New Complexity of Traveling Brain Waves in Memory Circuits
Researchers at UCSF have observed a new feature of neural activity in the hippocampus – the brain’s memory hub – that may explain how this vital brain region combines a diverse range of inputs into a multi-layered memories that can later be recalled.
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Brain Wave Recordings Reveal Potential for Individualized Parkinson’s Treatments
Pioneering neural recordings in patients with Parkinson’s disease by UCSF scientists are providing the groundwork for personalized brain stimulation to treat Parkinson’s and other neurological disorders.
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Brain Boosters: Can Puzzles and Pills Make Us Sharper?
Games and supplements claim to strengthen memory and cognition. Should you buy them?
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Smart Cell Therapies for Solid Cancers Ready to Move Toward Clinical Trials
Researchers at UCSF have demonstrated how to engineer smart immune cells that are effective against solid tumors, opening the door to treating a variety of cancers that have long been untouchable with immunotherapies.
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Large New Study Reveals Rates of Brain Abnormalities in Healthy Children
A large study of brain MRI scans from 11,679 children between the ages of 9 and 10 reviewed by UC San Francisco neuroradiologists identified potentially life-threatening conditions in 1 in 500
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Playing Virtual Reality Video Game May Boost Seniors’ Memory
Scientists at UCSF’s Neuroscape brain research center have developed a first-of-its-kind virtual reality video game that can improve memory in healthy, older adults.
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To Keep a Sharp Mind, Start Thinking of Heart Health in Your 20s
A new study led by UC San Francisco finds that young adulthood may be the most critical period to practice the healthy lifestyle habits that may protect the brain from cognitive decline decades later.
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A Better Way to Zap Our Brains
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Key Decision Point for Brain Development Identified
In a new study, UCSF and Stanford researchers have identified a central switch that appears to control when neural progenitor cells stop multiplying and start differentiating into mature neurons.
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Personalized Brain Stimulation Alleviates Severe Depression Symptoms
Depression is among the most common psychiatric disorders, affecting as many as 264 million people worldwide and leading to hundreds of thousands of deaths per year. But as many as 30 percent of patients do not respond to standard treatments such as medication or psychotherapy.
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Brain Cells Most Vulnerable to Alzheimer’s Disease Identified by Scientists
A team of researchers has identified for the first time the neurons that are among the first victims of Alzheimer’s disease.
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Seizure Risk Forecasted Days in Advance with Brain Implant Data
Patterns of brain activity can be used to forecast seizure risk in epilepsy patients several days in advance, according to a new analysis of data obtained from clinically approved brain implants by neuroscientists at UCSF, the University of Bern and the University of Geneva.
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Astonishing Animals That Illuminate Human Health
Giant lizards with superpowered hearts. Hairless rodents that don’t seem to age. Songbirds that babble like human babies. These and other scurrying, soaring, and slithering wonders are teaching scientists how our own bodies work – and how to fix them.
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Drug Reverses Age-Related Mental Decline Within Days
In the new study, UCSF researchers showed rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function.
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Children With Dyslexia Show Stronger Emotional Responses
Children with dyslexia who watched emotionally evocative videos showed increased physiological and behavioral responses when compared to children without dyslexia.
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Forest Fires, Cars, Power Plants Join List of Risk Factors for Alzheimer’s Disease
The study adds to a body of evidence indicating that pollution from cars, factories, power plants and forest fires joins established dementia risk factors like smoking and diabetes.
