Scientists Find Mechanism that Eliminates Senescent Cells
Scientists at UCSF are learning how immune cells naturally clear the body of defunct – or senescent – cells that contribute to aging and many chronic diseases
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University of California San Francisco
Give to UCSFScientists at UCSF are learning how immune cells naturally clear the body of defunct – or senescent – cells that contribute to aging and many chronic diseases
Pioneering neural recordings in patients with Parkinson’s disease by UCSF scientists are providing the groundwork for personalized brain stimulation to treat Parkinson’s and other neurological disorders.
Games and supplements claim to strengthen memory and cognition. Should you buy them?
Researchers at UCSF have demonstrated how to engineer smart immune cells that are effective against solid tumors, opening the door to treating a variety of cancers that have long been untouchable with immunotherapies.
A large study of brain MRI scans from 11,679 children between the ages of 9 and 10 reviewed by UC San Francisco neuroradiologists identified potentially life-threatening conditions in 1 in 500
Scientists at UCSF’s Neuroscape brain research center have developed a first-of-its-kind virtual reality video game that can improve memory in healthy, older adults.
Researchers at UCSF have confirmed that a different, long under-studied type of brain cell – astrocytes, named for their star-like shape – can influence how long and how deeply animals sleep.
A new study led by UC San Francisco finds that young adulthood may be the most critical period to practice the healthy lifestyle habits that may protect the brain from cognitive decline decades later.
This will be one of the first and largest studies to examine the impact of factors like age and stress on vaccination effectiveness.
In a new study, UCSF and Stanford researchers have identified a central switch that appears to control when neural progenitor cells stop multiplying and start differentiating into mature neurons.
A new study finds that inherited genetic variation plays a role in who is likely to benefit from checkpoint inhibitors, which release the immune system’s brakes so it can attack cancer.
A new study of autism risk genes by UCSF and UC Berkeley scientists implicates disruption in prenatal neurogenesis – a process in which specialized “progenitor” cells give rise to new brain cells – in the development of autism spectrum disorders.
Patients with severe COVID-19 produce antibodies that paradoxically shut down their immune system’s virus-fighting response just when they need it most.
Depression is among the most common psychiatric disorders, affecting as many as 264 million people worldwide and leading to hundreds of thousands of deaths per year. But as many as 30 percent of patients do not respond to standard treatments such as medication or psychotherapy.
A team of researchers has identified for the first time the neurons that are among the first victims of Alzheimer’s disease.
Patterns of brain activity can be used to forecast seizure risk in epilepsy patients several days in advance, according to a new analysis of data obtained from clinically approved brain implants by neuroscientists at UCSF, the University of Bern and the University of Geneva.
We asked several UCSF experts for a personal take on what will convince them that a vaccine is safe.
This type of test could be used as a check against possible errors generated by the standard tests that directly detect the SARS-CoV-2 virus, the scientists said.
Giant lizards with superpowered hearts. Hairless rodents that don’t seem to age. Songbirds that babble like human babies. These and other scurrying, soaring, and slithering wonders are teaching scientists how our own bodies work – and how to fix them.
Immunotherapies are a promising anticancer arsenal and work by mobilizing the immune system to recognize and destroy cancer cells. Currently, however, only a third of patients respond to
In the new study, UCSF researchers showed rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function.
Children with dyslexia who watched emotionally evocative videos showed increased physiological and behavioral responses when compared to children without dyslexia.
Every fall, Matt Jacobson relives his Parkinson’s diagnosis so future pharmacists perceive the patient behind the prescription.
The study adds to a body of evidence indicating that pollution from cars, factories, power plants and forest fires joins established dementia risk factors like smoking and diabetes.
Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research.