A simple urine test can diagnose and predict acute rejection in kidney transplants, leading to an opportunity for earlier detection and treatment, according to a new study by researchers at UCSF.
Administering stem cell or enzyme therapy in utero may be a path to alleviating some congenital diseases that often result in losing a pregnancy, according to a new study in mice by UCSF researchers. They showed that stem cells can enter the fetal brain during prenatal development and make up for cells that fail to make an essential protein.
UCSF scientists found that an early-life window of immune tolerance available to a normally harmless bacterial species is firmly closed to another, often pathogenic species — one that is a leading cause of drug-resistant skin infections in the U.S. and occasional source of “flesh-eating” necrosis.
In a breakthrough with important implications for the future of immunotherapy for breast cancer, UCSF scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.
UC San Francisco and the Translational Research Institute for Space Health are co-sponsoring the inaugural Space Health Innovation Conference to advance research and scientific understanding of how space travel impacts health.
UCSF Benioff Children’s Hospitals have successfully treated a months-old infant with a rare childhood leukemia using a targeted therapy approved for adults with inoperable liver cancer and advanced kidney cancer.
UCSF Benioff Children’s Physicians foundation signed a partnership agreement with Latitude Food Allergy Care to expand access to medical care for children with food allergies and provide an important referral option for clinicians whose patients require specialty food-allergy care.
This documentary, about “a renegade scientist’s visionary quest to find a cure for cancer,” features immunologist James Allison, PhD, a residency alumnus and a former member of the UCSF and UC Berkeley faculties. Allison overcame many obstacles en route to his discovery of the immune system’s role in defeating cancer – work that won him a 2018 Nobel Prize. Narrated by Woody Harrelson, the film includes interviews with several current UCSF researchers, including Max Krummel, PhD, who as a graduate student in Allison’s UC Berkeley lab led several of the key studies recognized by the Nobel.
A Phase 3 study has found that patients with Sickle Cell Disease (SCD) who took a daily dose of the novel drug voxelotor had less anemia and made healthier red blood cells than patients receiving a placebo.
Properly caring for the skin with a moisturizing cream may lower inflammation levels and potentially prevent age-related diseases, according to a new clinical pilot study.
UCSF scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally “invisible” to the immune system.
Researchers have discovered that the intestine is the source of immune cells that reduce brain inflammation in people with MS, and that increasing the number of these cells blocks inflammation entirely.
From sensory processing disorder to how CRISPR is being explored to bring new treatments to patients, these are the stories that most engaged our readers in 2018.
Scientists identified key ways Ebola, Dengue, and Zika viruses hijack the body’s cells, and they found at least one potential drug that can disrupt this process in human cells.
Thirty-five years after its launch, Ward 86 continues to be a global leader in HIV care and has significantly influenced milestones in treatment and prevention.
UCSF researchers have devised a CRISPR-based system called SLICE, which will allow scientists to rapidly assess the function of each and every gene in “primary” immune cells.
Using a mouse model, researchers showed that a drug that temporarily suppresses a key component of the brain’s immune system can prevent radiation-associated cognitive decline.
Scientists at UCSF have assembled a searchable database of normal human immunity that researchers can now use as an instant comparison group in studies of the immune system and immune dysfunction.