University of California San Francisco
Give to UCSFFor a conditioned response to become long-lasting requires brain cells to increase amounts of an insulating material called myelin, which may serve to reinforce and stabilize newly formed neural connections.
Survival may more than double for adults with glioblastoma, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor.
UCSF researchers are working on deep-brain stimulation technology that can be customized to the patient’s brain make up and their own brain’s feedback.
Understanding the biological differences that drive distinct symptoms of Alzheimer’s disease could lead to more personalized patient care and potentially therapies targeted to patients’ individual needs.
Leaders in dementia from Latin America joined community members from the Global Brain Health Institute, Alzheimer’s Association, the Tau Consortium, the National Institute of Health (NIH) and more at UCSF Mission Bay for the US-Latin American Networking on Dementia Symposium. Cohosted by GBHI and the UCSF Memory and Aging Center.
In a study of rats navigating a simple maze, neuroscientists at UCSF have discovered how the brain may generate such imagined future scenarios. The work provides a new grounding for understanding not only how the brain makes decisions but also how imagination works more broadly, the researchers say.
Widely used organoid models fail to replicate even basic features of brain development and organization, much less the complex circuitry needed to model complex brain diseases or normal cognition.
For 15 years, nobody could figure out what was making a young woman so sick. Then neurologist Michael Wilson, MD, tried a radical new test.
Scientists at UCSF are exploring how we can improve our bodies – now and in the future – with science that sounds like sci-fi.
English and Italian speakers with dementia-related language impairment experience distinct kinds of speech and reading difficulties based on features of their native languages.
A physically and mentally active lifestyle confers resilience to frontotemporal dementia, even in people whose genetic profile makes the eventual development of the disease virtually inevitable.
UCSF postdoctoral researcher for the first time succeeded in keeping a diverse array of glioblastomas alive in the lab using brain organoids
With the global population of seniors projected to reach 1.5 billion by 2050, it will be more important than ever to reduce the burden of age-related disease. In the future, science will allow us to intervene in the aging process to make this a reality, according to geriatrician John Newman.
Advances in medicine and public health have dramatically extended the lifespan of hearts, lungs, and other vital organs. But for women, the ovaries remain a stubborn exception. That may soon change, says fertility expert Marcelle Cedars.
Scientists have documented the influence of information overload on attention, perception, memory, decision-making, and emotional regulation. But the same technologies contributing to the cognition crisis could help solve it, argues neuroscientist Adam Gazzaley.
We are entering an era of brain-machine interfaces and genome-editing technology. When we can govern the very biology that makes us who we are, what will it mean to be human?
Brain imaging of pathological tau-protein reliably predicts the location of future brain atrophy in Alzheimer’s patients a year or more in advance.
No one can see the future, but that won’t stop us from trying. We asked UCSF faculty and alumni to score these predictions for likelihood and impact.
A drug that once helped obese adults lose weight, but was withdrawn from the market due to heart risks, may be safe and effective for children with a life-threatening seizure disorder called Dravet syndrome.
From international awards for high-caliber research to groundswell movements for social change, this past year was an eventful one for the UCSF community.