University of California San Francisco
Give to UCSFRamani is featured for co-inventing sci-Plex, a new technique that enables high-throughput chemical screening using single-cell RNA-sequencing as a read-out.
Using standard animal model of Down syndrome, scientists were able to correct the learning and memory deficits associated with the condition with drugs that target the body’s response to cellular stresses.
Cystic Fibrosis (CF) in Puerto Rico and the Dominican Republic is dominated by unusual gene mutations not often observed in previously studied CF populations. Majority of Dominican patients had no detectable mutations at all in the gene that is thought to drive 95 percent of CF cases.
The cause of the pancreatic inflammation plaguing a rural California family has been a medical mystery since it was first described 51 years ago. Now genetic sleuth-work by researchers from UC San Francisco and the University of Chicago has solved the mystery: pointing to a novel gene mutation as the cause of the family’s inherited pancreatitis.
Now in its sixth year, the Best Global Universities rankings focus on schools’ academic research and reputation.
The UCSF scientists who identified the two known human genes that promote “natural short sleep” have now discovered a third, and it’s also the first gene that’s ever been shown to prevent the memory deficits that normally accompany sleep deprivation.
UCSF study conducted in songbirds shows that what at first appear to be genetic constraints on birds’ song learning abilities could be largely eliminated by tailoring instruction to better match the birds’ inborn predispositions.
A new genetic test found that Quincy's aggressive blood cancer had an unusual mutation on the FLT3 gene. That gave Quincy’s doctors a life-saving idea.
UCSF Benioff Children’s Hospitals have successfully treated a months-old infant with a rare childhood leukemia using a targeted therapy approved for adults with inoperable liver cancer and advanced kidney cancer.
UCSF scientists who identified the only human gene known to promote “natural short sleep” have discovered a second.
Study shows that the adult-to-iPSC conversion process can mutate DNA found in mitochondria, causing mice and humans to reject iPSCs, and stem cell transplants more generally.
In a paper researchers describe a technique that uses a special version of CRISPR developed at UCSF to systematically alter the activity of genes in human neurons generated from stem cells, the first successful merger of stem cell-derived cell types and CRISPR screening technologies.
Advanced sleep phase that lures people to sleep at 8 p.m., enabling them to wake up as early as 4 a.m — previously believed to be very rare — may affect at least one in 300 adults.
A study of newborn infants has identified a compound produced by gut bacteria that appears to predispose certain infants to allergies and asthma later in life.
Brain damage associated with MS specifically targets a common class of brain cells called projection neurons
Today, our understanding of glioma subtypes has expanded to include the molecular and genetic variants that can influence a tumor’s development, prognosis, and response to treatment.
Unlike other gene mutations linked to autism, which are thought to alter brain development before birth, the newly identified changes in brain signaling may occur closer to the onset of autism symptoms in the first years of life.
A Phase 3 study has found that patients with Sickle Cell Disease (SCD) who took a daily dose of the novel drug voxelotor had less anemia and made healthier red blood cells than patients receiving a placebo.
The Laboratory for Genomic Research represents a novel hybrid model that brings together industrial and academic researchers under a single roof working on projects both together and independently.