Researchers screened a massive library of over 150 million virtual molecules and discovered the first drugs that selectively target one of two mammalian melatonin receptors that modulate sleep-wake cycles.
For a conditioned response to become long-lasting requires brain cells to increase amounts of an insulating material called myelin, which may serve to reinforce and stabilize newly formed neural connections.
The anonymous contribution will establish an endowment, providing a steady and lasting source of income to sustain the long-term vision of the current and future deans of the school and the future of oral health.
In a study of rats navigating a simple maze, neuroscientists at UCSF have discovered how the brain may generate such imagined future scenarios. The work provides a new grounding for understanding not only how the brain makes decisions but also how imagination works more broadly, the researchers say.
Researchers found that when default settings, showing a preset number of opioid pills, were modified downward, physicians prescribed fewer pills. Fewer pills could improve prescription practices and protect patients from developing opioid addictions.
Scientists from UCSF, UC Berkeley and Lawrence Berkeley National Laboratory have concluded an independent review of the appropriateness of the radiation testing protocols used by the California Department of Public Health and the U.S. Navy to assess radiation contamination at the Hunters Point Shipyard.
A single payer healthcare system would save money over time, likely even during the first year of operation, according to nearly two dozen analyses of national and statewide single payer proposals made over the past 30 years.
Pelvic examinations and cervical cancer screenings are no longer recommended for most females under age 21, but a new study has found that millions of young women are unnecessarily undergoing the tests.
A survey found that fewer than half of California pharmacies provided antibiotics and opioids disposal instructions meeting U.S. FDA guidelines, and just 10 percent followed the FDA’s preferred recommendation to take back unused medications from their customers.
A skin-lightening cream from Mexico has been found to have had a devastating effect on the central nervous system due to its highly toxic mercury levels, according to a UCSF-led report on a patient who remains unable to care for herself months after ceasing use of the product.
A drug that once helped obese adults lose weight, but was withdrawn from the market due to heart risks, may be safe and effective for children with a life-threatening seizure disorder called Dravet syndrome.
E-cigarette use significantly increases a person’s risk of developing chronic lung diseases like asthma, bronchitis, emphysema or chronic obstructive pulmonary disease, according to new UC San Francisco research, the first longitudinal study linking e-cigarettes to respiratory illness in a sample representative of the entire U.S. adult population.
Patients with ambiguous neurological symptoms, but no diagnosis, frequently go from specialist-to-specialist over a protracted period of time. The new clinic’s goal is to fast-forward the time lapses between appointments by enabling pre-diagnostic screening and expert consultations to take place in a single visit.