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Psilocybin Rewires the Brain for People with Depression

Scientists at UC San Francisco and Imperial College London found that psilocybin fosters greater connections between different regions of the brain in depressed people, freeing them up from long-held patterns of rumination and excessive self-focus.

A graphic rendering of a brain’s landscape that measures connections between areas of the brain that affect thought patterns. In this rendering of a brain with depression, high peaks are in yellow, with deeper spaces in purple.

UCSF Dyslexia Researchers Develop Tool to Flag Early Reading Challenges

UCSF researchers have developed a digital tool to flag early reading challenges that may lead to dyslexia, and it could be in widespread use in California public schools by 2023. Governor Gavin Newsom is proposing $10 million in the state budget for the project.

School proctors with school children using Multitudes assessment tool on ipads

Looking to the Cell’s Power Generators for Clues to Depression

Hoping to discover a new approach to treating depression, UCSF researchers looked at mitochondrial proteins and found that people with untreated depression have significantly lower levels of these proteins. New hypotheses emerge about the relationship between depression and the function of the brain’s energy-hungry neurons.

Microscopic image of fibroblast cells from mouse. Nucleus is in blue and mitochondria is in green

UCSF and UCLA Receive $41.5M to Address Health Impacts of Toxic Stress

UCLA and UCSF are collaborating with the California Department of Health Care Services and Office of the California Surgeon General on a multi-campus initiative addressing the impact of Adverse Childhood Experiences (ACEs) and other causes of toxic stress on health.