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Treating Severe Depression with On-Demand Brain Stimulation

UCSF Health physicians have successfully treated a patient with severe depression by tapping into the specific brain circuit involved in depressive brain patterns and resetting them using the equivalent of a pacemaker for the brain.

Patient Sarah visits her doctor's office where they check on her deep brain stimulation DBS implant

Q&A: Building a Speech Prosthetic for a Paralyzed Man

Following groundbreaking work on a “speech neuroprosthesis” that enabled a paralyzed man to communicate using his brain signals, the lab team answered public questions about brain-computer interfaces and the limitations of translating brain signals into code.

Man using neural prosthesis to translate his thoughts into words on a screen when prompted

Dual-Drug Therapy Shows Promise for Treating Alcohol Use Disorder

UCSF researchers have leveraged two new molecules, one of which is currently in clinical oncology trials, to devise a dual-drug therapy for alcohol use disorder (AUD), without the side effects or complications associated with current treatment regimens.

For Concussion Patients, CTs Offer Window into Recovery

CT scans for patients with concussion provide critical information about their risk for long-term impairment and potential to make a complete recovery – findings that underscore the need for physician follow-up.

Black-and-white CT images of brains with signs of concussion

“Neuroprosthesis” Restores Words to Man with Paralysis

Researchers at UC San Francisco have successfully developed a “speech neuroprosthesis” that has enabled a man with severe paralysis to communicate in sentences, translating signals from his brain to the vocal tract directly into words that appear as text on a screen.

Man using neural prosthesis to translate his thoughts into words on a screen when prompted