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CryoEM Study Captures Opioid Signaling in the Act

Scientists have used ultra-high-resolution cryo–electron microscopy to capture the most detailed portrait ever of an opioid drug triggering the biochemical signaling cascade that gives it its power.

Streets of Pain

UCSF public health researcher Daniel Ciccarone, MD, shares his quest to understand the nation’s opioid epidemic, one user at a time.

Daniel Ciccarone stands on a city street.