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Biophysicist Aashish Manglik, MD, PhD, is the newly awarded 2024 Bowes Biomedical Investigator. With the award, he hopes to further the intersection of his GPCR research and neuropsychiatric diseases.
UCSF researchers discover how gabapentin interacts with calcium channels, opening doors for more effective treatments in epilepsy and Lupus by influencing channel biogenesis.
UCSF faculty members Walter G. Gonzalez and Angela Phillips have been selected as Howard Hughes Medical Institute (HHMI) Freeman Hrabowski Scholars. With up to $8.6 million in support, they will conduct research, create inclusive lab environments, and make a significant impact on the future of science. Both scholars are committed to fostering diversity and promoting scientific breakthroughs.
Because proteins can adapt to extremes, Margaux Pinney, PhD, believes they can show how living organisms might adapt to climate change.
Research shows that after cells are subjected to certain stressful treatments, they appear to gain a new “superpower” that allows them to grow twice as fast as normal — a feature the authors call “supergrowth.”
UCSF researchers developed a strategy for targeting a key molecule implicated in Parkinson’s disease, opening up a potential new treatment strategy for the currently incurable movement disorder.
Hana El-Samad’s research may one day make it possible to take a broken cell and bring it back to health by dynamically sensing its pathology and fixing it.
A new study finds that a common cancer-causing mutation in a GTPase called Gαs subverts the model for this type of growth switch in cancer.
UCSF researchers have shown that an experimental brain boosting drug, ISRIB, acts like a molecular staple, pinning together parts of a much larger protein involved in cellular stress.
UCSF’s Peter Walter is among nine University of California inventors and innovators who have been selected to become National Academy of Inventors fellows.
UCSF researchers have discovered that two molecular partners interact at synapses to maintain stable neuronal function.
A new study by UCSF researchers revealed the intriguing possibility that HP1α binds to stretches of DNA and pulls it into droplets that shield the genetic material inside from the molecular machinery of the nucleus that reads and translates the genome.
Researchers at UCSF and elsewhere are turning to virtual experiments for the initial steps of drug development.
