3-D Imaging Reveals Secrets of Immune Cells’ Agility
Newly developed microscopy techniques have allowed UC San Francisco researchers to observe white blood cells in action in unprecedented detail.
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Blunting CRISPR’s ‘Scissors’ Gives New Insight into Autoimmune Disorders
Research team led by University of California scientists has used a modified version of the gene-editing technique CRISPR to find enhancers by prompting them into action.
Common Use of Antibiotics in Cells Grown for Research Could Distort Tests
A new study by UCSF researchers raises a red flag against adding antibiotics when growing cells in labs, finding that it can induce unintentional genetic changes in the cells and distort test results.
Finding Better Ways to Reduce Serious Drug Side Effects
Two UCSF School of Pharmacy faculty members, whose research and clinical practice have focused on the identification and minimization of side effects, have pinpointed routes for improvement.
Reversing Memory Failure Caused by TBI: 6 Questions for Neuroscientist Susanna Rosi
UCSF neuroscientists answered questions about a molecule that reverses severe memory and learning impairments in mice with traumatic brain injury.
ShangPharma Innovation and UCSF Announce Strategic Research Collaboration
In a new collaboration, ShangPharma Innovation, Inc. is providing funding and other support to scientists at UC San Francisco to accelerate the development of promising life science inventions.
Tiny Cellular Antennae Key to Fat Formation in Muscle
Scientists at UCSF have shown that cellular antennae called cilia, found on fat-forming cells interspersed in muscle, play a key role in this muscle-to-fat transformation.
Drug Reverses Memory Failure Caused by Traumatic Brain Injury
UCSF scientists used an experimental drug to completely reverse severe learning and memory impairments caused by traumatic brain injury in mice.
Rare Cells are ‘Window Into the Gut’ for the Nervous System
Specialized cells in the gut sense potentially noxious chemicals and trigger electrical impulses in nearby nerve fibers, according to a new study led by UCSF scientists.
From Strands to Droplets: New Insights into DNA Control
A new study by UCSF researchers revealed the intriguing possibility that HP1α binds to stretches of DNA and pulls it into droplets that shield the genetic material inside from the molecular machinery of the nucleus that reads and translates the genome.
Research Reveals How RNA Gums Up Cell Nucleus in Huntington’s, Other Neurodegenerative Disorders
UCSF researchers have drawn a link between genetic abnormalities in neurodegenerative diseases and the formation of RNA foci, work the scientists said may open avenues to the development of new drug treatments.
New Tool Illuminates Cell Signaling Pathways Key to Disease
In a major advance for fundamental biological research, UCSF scientists have developed a tool capable of illuminating previously inscrutable cellular signaling networks.
How Computers are Searching for Drugs of the Future
Researchers at UCSF and elsewhere are turning to virtual experiments for the initial steps of drug development.
Deworming Pill May Be Effective in Treating Liver Cancer
UCSF researchers have used data-mining computational tools to identify a treatment for hepatocellular carcinoma, a cancer associated with underlying liver disease and cirrhosis that often only becomes symptomatic when it is very advanced.
