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Healthy Sleep May Rely on Long-Overlooked Brain Cells

Researchers at UCSF have confirmed that a different, long under-studied type of brain cell – astrocytes, named for their star-like shape – can influence how long and how deeply animals sleep.

microscopic image of Astrocyte

Key Decision Point for Brain Development Identified

In a new study, UCSF and Stanford researchers have identified a central switch that appears to control when neural progenitor cells stop multiplying and start differentiating into mature neurons.

Microcopic image of mouse brain with cells colored in red, yellow, green, and blue

‘Hidden Biological Link’ Among Autism Genes Revealed in Study

A new study of autism risk genes by UCSF and UC Berkeley scientists implicates disruption in prenatal neurogenesis – a process in which specialized “progenitor” cells give rise to new brain cells – in the development of autism spectrum disorders.

microscopic image of a tadpole showing its central nervous system

Personalized Brain Stimulation Alleviates Severe Depression Symptoms

Depression is among the most common psychiatric disorders, affecting as many as 264 million people worldwide and leading to hundreds of thousands of deaths per year. But as many as 30 percent of patients do not respond to standard treatments such as medication or psychotherapy.

Seizure Risk Forecasted Days in Advance with Brain Implant Data

Patterns of brain activity can be used to forecast seizure risk in epilepsy patients several days in advance, according to a new analysis of data obtained from clinically approved brain implants by neuroscientists at UCSF, the University of Bern and the University of Geneva.

Astonishing Animals That Illuminate Human Health

Giant lizards with superpowered hearts. Hairless rodents that don’t seem to age. Songbirds that babble like human babies. These and other scurrying, soaring, and slithering wonders are teaching scientists how our own bodies work – and how to fix them.

Photo of a Komodo dragon with its tongue out, with bright colored lights on a black background.

Drug Reverses Age-Related Mental Decline Within Days

In the new study, UCSF researchers showed rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function.