Dozens of Gut Bacteria Associated with Multiple Sclerosis
Researchers have found significant differences between the gut bacteria profiles of multiple sclerosis (MS) patients and healthy individuals, showing new pathways for potential treatment.
University of California San Francisco
Give to UCSF
Physical Activity May Still Not Match Pre-Covid 19 Pandemic Levels
A UCSF study found that step counts, a measure of physical activity, were markedly lower early in the COVID-19 pandemic than pre-pandemic and remained lower on average in the two years following the onset of the global pandemic.
Older Homeless People Are At Great Risk of Dying
The study, funded by the National Institute on Aging, recruited people who were 50 and older and homeless, and followed them for a median of 4.5 years. By interviewing people every six months about their health and housing status, researchers were able to examine how things like regaining housing, using drugs, and having various chronic conditions, such as diabetes, affected their risk of dying.
Eye Movements in REM Sleep Mimic Gazes in the Dream World
When our eyes move during REM sleep, we’re gazing at things in the dream world our brains have created, according to a new study by UCSF researchers. The findings shed light not only into how we dream, but also into how our imaginations work.
A Cellular Engineering Breakthrough: High-Yield CRISPR Without Viral Vectors
A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications. The approach, developed at Gladstone Institutes and UC San Francisco (UCSF), lets scientists introduce especially long DNA sequences to precise locations in the genomes of cells at remarkably high efficiencies without the viral delivery systems that have traditionally been used to carry DNA into cells.
UCSF Survey Finds Vast Majority Comfortable with Campus Climate
A campuswide survey of members of the UCSF community finds that respondents are generally positive about the University’s working and learning environment overall with 70% indicating that they feel either “comfortable” or “very comfortable” while 11% feel “uncomfortable” or “very uncomfortable.”
Giving Immunotherapy Cells Resilience to Pass the ‘Stress Test’
T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.
Reprogramming the Brain’s Cleaning Crew to Mop Up Alzheimer’s Disease
The discovery of how to shift damaged brain cells from a diseased state into a healthy one poses a potential new path to treating Alzheimer’s and other forms of dementia, according to a new study from UCSF researchers.
Blood Tests in Newly Brain-Injured Patients Predict Death, Severe Disability
Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UCSF, the University of Pennsylvania and the University of Michigan.
UCSF Joins $200 Million Global Tuberculosis Consortium
UCSF researchers are part of a $200 million global consortium to develop new diagnostics, therapeutics, containment and control strategies to reduce the suffering from tuberculosis (TB) around the world.
