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Tweaked CRISPR in Neurons Gives Scientists New Power to Probe Brain Diseases

In a paper researchers describe a technique that uses a special version of CRISPR developed at UCSF to systematically alter the activity of genes in human neurons generated from stem cells, the first successful merger of stem cell-derived cell types and CRISPR screening technologies.

microscopic image of neurons

The Case of the Confused Grandfather

For months, the 78-year-old had been behaving strangely. Fearing the worst, his family consulted UCSF neurologist Georges Naasan, MD.

Illustration of a male doctor holding a clipboard and pen, looking at brain scans on a wall.