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Innovative UC Health Tool Leads to Better Blood Pressure Control

A special program developed by the University of California Health system and adopted at all six UC academic medical centers has been effective in reducing hypertension in patients and could be used by other health systems looking to standardize chronic disease care.

A close-up shot of a person’s arm extended as a health practitioner measures their blood pressure with an at-home blood pressure monitor.

How the Immune System Triggers a Loss of Appetite

A new study traces the molecular pathway connecting the gut immune system to the brain during a parasitic infection, explaining how the immune system triggers a loss of appetite.

A microscopic image shows several finger-like structures called villi against a black background. The villi are filled with a glowing yellow network, and small, red almond-shaped cells—known as tuft cells—are scattered throughout the network.

How the Body Senses Cold Has Been a Mystery – Until Now

TRPM8, a key cold-sensing protein in nerve cells, activates to send “cold” signals to the brain when exposed to low temperatures or cooling sensations like menthol. New research from UCSF reveals how TRPM8 changes shape in response to cold, offering insights into cold sensitivity, pain conditions, and why birds are less sensitive to cold than mammals.

A 3D molecular rendering of a TRPM8 protein, shown as a complex, bumpy mass in shades of light blue and grey against a solid white background. In the upper-left corner, the structure appears to be breaking apart or dispersing into small, scattered fragments.

Is Your Brain Aging Faster Than You Are? Sleep May Hold the Key

Poor sleep is associated with an increased risk for dementia, but many sleep studies have had inconsistent results. For the first time, used AI to analyze tiny electrical signals in the brain of 7,000 participants healthy participants to calculate “brain age." They find that dementia risk increases significantly when the brain age exceeds actual age.

A person seen from behind sitting in a red chair and wearing a black EEG head-cap with numerous yellow sensors and wires. They are looking at a large screen in a dark room that displays a glowing, translucent blue and orange 3D visualization of a human brain.

Haven’t Heard of Lynch Syndrome? You’re Not Alone.

The UCSF Lynch Syndrome Center is a leading Northern California clinic specializing in Lynch syndrome, a common genetic condition increasing the risk of colon cancer and other cancers. The center offers comprehensive, multidisciplinary care, advanced cancer screening, and cutting-edge treatments, including an NIH-funded vaccine trial, to nearly 1,000 patients.

An illustration of a gloved hand holding a petri dish under a microscope, where a glowing yellow immune cell targets several red, spiky cancer cells.