New research by UCSF stem cell biologists has revealed that a DNA-binding protein called Foxd3 acts like a genetic traffic signal, holding that ball of undifferentiated cells in a state of readiness for its great transformation in the third week of development.
UCSF scientists describe capturing and studying individual metastatic cells from human breast cancer tumors implanted into mice as the cells escaped into the blood stream and began to form tumors elsewhere in the body.
Zev Gartner is working to building a fully functioning 3-D human breast tissue that will allow him to test potential cancer therapies, an innovation that's earned him a spot among Popular Science's "Brilliant 10" this year.
Emmanuelle Passegué’s passion for blood is focused on rejuvenation and longer life. This may sound like something out of a vampire story, but her work is rooted in a different kind of mystery: one that could hold the key to how well we age and respond to diseases.
UCSF researchers have for the first time developed a method to precisely control embryonic stem cell differentiation with beams of light, enabling them to be transformed into neurons in response to a precise external cue.