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Aging HIV patients whose infection has not evolved into full-blown AIDS may be at risk for developing a chronic dementia similar to Alzheimer's disease, according to researchers at the San Francisco Veterans Affairs Medical Center and UCSF.
Removal of an enzyme that regulates the activity of many proteins can suppress key features of Alzheimer's disease in experimental models, researchers at the Gladstone Institute of Neurological Disease (GIND) recently reported in the Journal of Neuroscience (May 12, 2004).
Researchers at the San Francisco Veterans Affairs Medical Center and UCSF have discovered that an important protein normally secreted by macrophages, the scavenger cells of the immune system, is secreted at significantly reduced levels in patients with HIV-related dementia.
Middle-aged patients with several risk factors for heart disease are twice as likely to develop dementia in old age as middle-aged patients with only one risk factor, according to a study that will be presented at the American Academy of Neurology 56th Annual Meeting ...
Promising research into the causes of Alzheimer's disease, with an emphasis on the roles of such proteins as amyloid-beta and apolipoprotein E, will be the subject of a plenary session presentation on April 29 at the American Academy of Neurology (AAN) 56th Annual Meeting in San Francisco.
Cholesterol-busting statins, the largest-selling prescription drugs in the U.S., may protect older people from blindness, a new study shows. Aspirin also appears to provide significant protection, according to the research.
Researchers at the Gladstone Institute of Neurological Disease have identified processes that may explain how a key protein, apolipoprotein E4 (apoE4), contributes to the development of Alzheimer's disease.
UCSF researchers are conducting a study to determine if it is safe and effective to use smoked marijuana in combination with opioid pain medications to treat cancer pain.
UCSF researchers found no harmful changes in HIV virus levels in patients on combination antiretroviral therapy in a safety study looking at both smoked marijuana and dronabinol, an oral medical cannabinoid.
UCSF researchers found no harmful changes in HIV virus levels in patients on combination antretroiviral therapy in a safety study looking at both smoked marijuana and dronabinol, an oral medical cannabinoid.
Until now, scientists have been unable to distinguish between dementia caused by Alzheimer's disease and that caused by poor blood flow to the brain.
A protein that senses changes in calcium levels can be used to estimate the extent of cognitive deficits caused by toxic amyloid peptides found in Alzheimer brains, researchers at the Gladstone Institute of Neurological Disease (GIND) and the University of California have discovered.
Philip Morris tobacco company launched a hidden campaign in the 1990s to change the standards of scientific proof needed to demonstrate that secondhand smoke was dangerous...
SAN DIEGO -- Women who have a particular gene sequence are at a higher risk of developing cognitive impairment and Alzheimer's disease, according to a study from researchers at UCSF and the Veterans Affairs Medical Center (SFVAMC).
A UCSF study of the migration patterns of underrepresented minority Californians in medicine found that those who attend medical schools in the state are more likely to enter residency programs in California and remain in the state to practice.
Some animal studies have shown that aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) have an anti-tumor effect in the colon. Also, some studies in people suggest that these drugs may decrease the risk of colorectal cancer.
Patients with sickle cell disease experience pain and organ failure when their abnormal red blood cells (erythrocytes) block flow through small vessels... blockage may be initiated by blood cells sticking to blood vessel walls.
For-profit nursing homes are much more likely than their non-profit counterparts to be cited for deficient quality, according to a UCSF/Harvard study.
Researchers at the Gladstone Institute of Virology and Immunology have now discovered a new pathway by which the cell regulates the activity of NF-kB, setting the stage for new therapeutic approaches.
Potentially life threatening seizures can be safely treated by paramedics using injections of Valium or similar benzodiazepine drugs en route to the hospital, rather than waiting for hospital staff to administer the drugs.
UCSF researchers have identified the most useful dimensions for measuring and reporting nursing home quality.