How Do Middle-Aged Folks Get Dementia? It Could Be These Proteins
UCSF researchers have found clues about how frontotemporal dementia develops that could lead to new diagnostics and get more patients into clinical trials.
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How ‘Magic Mushrooms’ Could Help Parkinson’s Disease Patients
A first-of-its-kind study tested the safety of psilocybin on patients with mild to moderate Parkinson’s disease and found that patients experienced clinically significant improvements in mood, cognition, and motor function that lasted for weeks after the drug was out of their systems.
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Breakthrough Multiple Sclerosis Therapy by UCSF Doctor Transforms Treatment for Millions
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Bay Area Patients Among First in U.S. To Receive Life-Changing Parkinson’s Treatment
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Stephen Hauser Wins Breakthrough Prize for Role in Redefining MS
Neuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences.
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Is Increased Sleepiness in Our 80s Tied to Higher Dementia Risk?
A study followed the sleep patterns of older female participants to see if specific patterns of change were associated with a higher risk of dementia. The participants, whose average age was 83, were monitored by wrist devices that track movement and time spent asleep.
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NIH Funding Drives UCSF’s Pursuit of Better Health for All
UCSF received $815 million in awards from the National Institutes of Health (NIH) last year for research that will improve the lives of patients in the U.S. and around the world.
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How a Paralyzed Man Moved a Robotic Arm with His Thoughts
A paralyzed man was able to move a robotic arm and fingers simply by imagining himself doing so, with the help of brain signals decoded through a computer.
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How to Build Bold Thinking to Foster Scientific Breakthroughs
Martin Kampmann, PhD, and Anna Victoria Molofsky, MD, PhD, are the 2025 recipients of the Bowes Biomedical Investigator award, which supports scientists who take novel approaches and have the potential to make significant contributions to biomedicine. Recipients receive $1.25 million over five years.
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Aging Women’s Brain Mysteries Are Tested in Trio of Studies
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Napping More as You Get Older? Here’s Why That May Not Be a Good Thing
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Human Chromosomes Evolved at Hyperspeed to Give Us Better Brains
How did humans evolve brains capable of complex language, civilization, and more? Scientists at UC San Francisco recently found that parts of our chromosomes have evolved at breakneck speeds to give us an edge in brain development compared to apes.
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This New Treatment Can Adjust to Parkinson’s Symptoms in Real Time
The FDA has approved an adaptive deep brain stimulation (aDBS) treatment for people with with Parkinson’s disease, making this groundbreaking technology available to people nationwide.
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Jumbled Proteins Paint a Bold Target on the Backs of Brain Tumors
UCSF scientists have found that some cancers, like brain cancer, make unique, jumbled proteins that make them stand out. These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors.
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‘Healthy’ Vitamin B12 Levels Not Enough to Ward Off Neuro Decline
A study found that B12 requirements may be too low for some people, putting them at risk for cognitive decline.
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How a UCSF Scientist Helped Ban a Chemical Connected to Parkinson’s
A new EPA ban on TCE, a common industrial cleaning agent and contaminant, begins this year. UCSF’s Samuel Goldman, who led groundbreaking research to link TCE to Parkinson’s Disease, talks about the health risks.
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Delayed REM Sleep Could Be an Early Sign of Alzheimer’s
Delayed REM sleep was found to be linked to higher Alzheimer’s risk. Healthy sleep habits and treatments may help mitigate risks.
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For Women With MS, Mobility Takes Step Backward at Menopause
A new study found that menopause can speed up the progression of multiple sclerosis (MS), affecting mobility and cognitive ability.
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Why Some People Can Get Away With Only a Little Sleep Every Night
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The Future of Neuroscience: Building a Silicon Brain
A digital twin of a human mind? It isn’t science fiction.
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48 UCSF Researchers Are Honored for Their High-Impact Science
Nearly 50 UCSF researchers have been named to Clarivate’s list of most influential scientists for 2024.
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How Optogenetics Can Put the Brakes on Epilepsy Seizures
A technique involving the use of light pulses to prevent seizure-like activity in neurons could one day become a new, non-invasive treatment for epilepsy.
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This AI Tool Helps Neurosurgeons Find Sneaky Cancer Cells
An AI-based diagnostic system reveals cancerous tissue that may not otherwise be visible during brain tumor surgery. This enables neurosurgeons to remove it while the patient is still under anesthesia – or treat it afterwards with targeted therapies.
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1 Genomic Test Can Diagnose Nearly Any Infection
A decade-long effort has resulted in a new, rapid genomic test to diagnose rare infectious diseases in the brain and lungs.
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Cutting-Edge Test Uses DNA Sequencing to Yield Diagnoses for Some Medical Mysteries
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How this ‘Switchable’ CAR-T Therapy Sets its Sights on Deadly Brain Cancer
In June, UCSF treated its first patient with E-SYNC, its first homegrown CAR-T therapy, one of the first to show promise in treating certain types of brain cancers. This story builds on previous coverage to provide an overview of CAR-T therapy, accessibility and future horizons of applications in cancer and other illnesses like HIV.
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Poor Sleep in Middle Age Could Affect the Brain in a Surprising Way, Study Finds
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Poor Sleep in Midlife Is Linked to Faster Brain Atrophy
Poor sleep in midlife, like difficulty falling asleep or waking early, may accelerate brain atrophy linked to dementia, a UCSF study finds.
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Yes, Dyslexia Can Be Genetic. But Genes Aren’t the Only Factor to Consider.
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New Hope for Progressive Supranuclear Palsy with Innovative Trial
A clinical trial that will test three drugs concurrently, and could include more, represents new hope for patients with progressive supranuclear palsy (PSP), an incurable neurodegenerative disorder that usually kills within seven years after symptoms start.
