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Surgical Procedure Helps Cancer Patients Face Themselves Again

For patients with skin cancer & facial sarcoma, reconstructing the face with skin grafted from the leg may result in poor color match. A new technique pioneered by UCSF surgeons uses pigmented tissue to achieve a better match.

stock images shows IV drip and pediatric patient in a hospital bed

Looking to the Cell’s Power Generators for Clues to Depression

Hoping to discover a new approach to treating depression, UCSF researchers looked at mitochondrial proteins and found that people with untreated depression have significantly lower levels of these proteins. New hypotheses emerge about the relationship between depression and the function of the brain’s energy-hungry neurons.

Microscopic image of fibroblast cells from mouse. Nucleus is in blue and mitochondria is in green

How Cells Multitask: The Magic of Molecular Switches

Researchers at UCSF’s Quantitative Biosciences Institute (QBI) have observed how molecular switches regulate many different biological processes simultaneously. Their findings may shed light on how disease mutations operate, offering new ways to target malfunctioning switches and prevent illness.

Looking Beyond DNA to See Cancer with New Clarity

Researchers at UCSF and UC San Diego have mapped out how hundreds of mutations involved in two types of cancer affect the activity of proteins that are the ultimate actors behind the disease.

microscopic images of breast cancer cells